Stimulin
Generic Name
Stimulin
Manufacturer
MediCare Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| stimulin 1 mg tablet | ৳ 3.01 | ৳ 30.10 |
Description
Overview of the medicine
Stimulin 1 mg Tablet is a central nervous system stimulant primarily used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy. It helps improve focus, attention, and reduce impulsivity in ADHD, and manage excessive daytime sleepiness in narcolepsy.
Uses & Indications
Dosage
Adults
For ADHD: Initially 1 mg once daily, adjusted based on response up to a maximum of 5 mg/day. For Narcolepsy: 1-2 mg once or twice daily, adjusted as needed.
Elderly
Use with caution; lower initial doses may be required. Monitor for cardiovascular effects.
Renal_impairment
No specific dose adjustment guidelines; use with caution. Consider lower doses if severe impairment.
How to Take
Take Stimulin 1 mg Tablet orally, usually in the morning with or without food. Avoid taking it late in the day to prevent sleep disturbances.
Mechanism of Action
Stimulin is believed to work by increasing the levels of certain neurotransmitters, such as dopamine and norepinephrine, in the brain. This enhancement helps to improve attention, decrease impulsivity, and reduce hyperactivity in patients with ADHD, and promote wakefulness in narcolepsy.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Excreted mainly in urine as metabolites and unchanged drug.
Half life
Approximately 4-6 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract.
Metabolism
Primarily hepatic metabolism via CYP450 enzymes.
Side Effects
Contraindications
- Hypersensitivity to Stimulin or any component of the tablet
- Advanced arteriosclerosis
- Symptomatic cardiovascular disease
- Moderate to severe hypertension
- Hyperthyroidism
- Glaucoma
- Anxiety, tension, or agitation
- History of drug abuse
- Concurrent use or within 14 days of discontinuing MAO inhibitors
Drug Interactions
MAO Inhibitors
Concurrent use can cause hypertensive crisis. Avoid within 14 days.
Acidifying agents
May decrease Stimulin absorption.
Antihypertensives
Stimulin may decrease the hypotensive effect of these drugs.
Antacids/Alkalinizing agents
May increase Stimulin absorption, leading to higher plasma levels.
Tricyclic Antidepressants (TCAs)
May increase cardiovascular risk.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include restlessness, tremor, hyperreflexia, rapid respiration, confusion, aggression, hallucinations, panic states, hyperpyrexia, rhabdomyolysis, and convulsions, followed by coma. Cardiovascular effects can include arrhythmias, hypertension or hypotension, and circulatory collapse. Gastric lavage and activated charcoal may be used. Supportive care, including sedation with benzodiazepines, is recommended for severe agitation or seizures. Monitor cardiovascular and respiratory function.
Pregnancy & Lactation
Stimulin is generally not recommended during pregnancy or breastfeeding due to potential risks to the fetus/infant. Discuss the risks and benefits with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Side Effects
Contraindications
- Hypersensitivity to Stimulin or any component of the tablet
- Advanced arteriosclerosis
- Symptomatic cardiovascular disease
- Moderate to severe hypertension
- Hyperthyroidism
- Glaucoma
- Anxiety, tension, or agitation
- History of drug abuse
- Concurrent use or within 14 days of discontinuing MAO inhibitors
Drug Interactions
MAO Inhibitors
Concurrent use can cause hypertensive crisis. Avoid within 14 days.
Acidifying agents
May decrease Stimulin absorption.
Antihypertensives
Stimulin may decrease the hypotensive effect of these drugs.
Antacids/Alkalinizing agents
May increase Stimulin absorption, leading to higher plasma levels.
Tricyclic Antidepressants (TCAs)
May increase cardiovascular risk.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include restlessness, tremor, hyperreflexia, rapid respiration, confusion, aggression, hallucinations, panic states, hyperpyrexia, rhabdomyolysis, and convulsions, followed by coma. Cardiovascular effects can include arrhythmias, hypertension or hypotension, and circulatory collapse. Gastric lavage and activated charcoal may be used. Supportive care, including sedation with benzodiazepines, is recommended for severe agitation or seizures. Monitor cardiovascular and respiratory function.
Pregnancy & Lactation
Stimulin is generally not recommended during pregnancy or breastfeeding due to potential risks to the fetus/infant. Discuss the risks and benefits with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date
Availability
Available in pharmacies and hospitals
Approval Status
Approved by DGDA
Patent Status
Patent expired, generic available
Clinical Trials
Extensive clinical trials have demonstrated the efficacy and safety of Stimulin in the treatment of ADHD and narcolepsy. Ongoing post-market surveillance continues to monitor long-term outcomes.
Lab Monitoring
- Monitor blood pressure and heart rate regularly.
- Periodically assess growth in pediatric patients.
- Liver and kidney function tests for prolonged use or in patients with pre-existing conditions.
Doctor Notes
- Assess cardiovascular status thoroughly before initiating Stimulin and periodically during treatment.
- Monitor for signs of abuse, misuse, or diversion.
- Consider drug holidays for pediatric patients to assess growth and reduce tolerance development.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Do not crush, chew, or break the tablet; swallow it whole.
- Inform your doctor about all other medications, supplements, and herbal products you are taking.
- Avoid alcohol consumption while taking Stimulin.
- Report any severe side effects, especially chest pain, shortness of breath, or fainting, immediately to your doctor.
Missed Dose Advice
If a dose is missed, take it as soon as you remember, unless it is too late in the day (e.g., late afternoon or evening). Do not double the dose to catch up. If it's close to the next scheduled dose, skip the missed dose and resume your regular dosing schedule.
Driving Precautions
Stimulin may cause dizziness, blurred vision, or affect judgment. Patients should be cautious when driving or operating machinery until they know how the medicine affects them.
Lifestyle Advice
- Maintain a regular sleep schedule to help manage sleep disturbances.
- Engage in regular physical activity to support overall well-being.
- Adopt a balanced diet.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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