Suconal
Generic Name
Sertraline Hydrochloride
Manufacturer
MediPharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| suconal 1 cream | ৳ 47.54 | N/A |
Description
Overview of the medicine
Suconal (Sertraline Hydrochloride) is an antidepressant medication used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder, and social anxiety disorder.
Uses & Indications
Dosage
Adults
Initial 50 mg once daily, may increase up to 200 mg daily.
Elderly
Lower starting doses or slower titration may be considered.
Renal_impairment
No dosage adjustment generally required for mild to moderate impairment; caution for severe impairment.
How to Take
Orally, once daily, with or without food. Can be taken in the morning or evening.
Mechanism of Action
Sertraline selectively inhibits the reuptake of serotonin (5-HT) by the presynaptic neuron, thereby potentiating serotonergic activity in the central nervous system.
Pharmacokinetics
Onset
Therapeutic effects may take 2-4 weeks to become apparent.
Excretion
Mainly via urine and feces as metabolites.
Half life
Approximately 26 hours for sertraline, 66 hours for N-desmethylsertraline (active metabolite).
Absorption
Well absorbed orally; peak plasma concentrations reached in 4.5-8.4 hours.
Metabolism
Extensively metabolized in the liver, primarily by CYP2C19, to N-desmethylsertraline.
Side Effects
Contraindications
- Concomitant use with MAOIs
- Hypersensitivity to sertraline
Drug Interactions
MAOIs
Risk of serotonin syndrome.
Pimozide
Increased pimozide levels.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include somnolence, vomiting, tachycardia, tremor, agitation. Management is supportive and symptomatic; no specific antidote.
Pregnancy & Lactation
Category C for pregnancy. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Excreted in breast milk, use with caution during lactation.
Side Effects
Contraindications
- Concomitant use with MAOIs
- Hypersensitivity to sertraline
Drug Interactions
MAOIs
Risk of serotonin syndrome.
Pimozide
Increased pimozide levels.
Storage
Store below 30°C in a dry place, away from light. Keep out of reach of children.
Overdose
Symptoms include somnolence, vomiting, tachycardia, tremor, agitation. Management is supportive and symptomatic; no specific antidote.
Pregnancy & Lactation
Category C for pregnancy. Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Excreted in breast milk, use with caution during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by regulatory bodies
Patent Status
Patent expired, generic available
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated efficacy and safety in various indications.
Lab Monitoring
- No routine lab monitoring required, but monitor for hyponatremia in at-risk patients.
Doctor Notes
- Advise patients on delayed onset of action.
- Monitor for suicidal ideation, especially at the start of treatment or dose changes.
Patient Guidelines
- Do not stop taking the medicine suddenly without consulting your doctor.
- Avoid alcohol consumption.
- Report any worsening of depression or suicidal thoughts.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose.
Driving Precautions
May cause drowsiness or dizziness; exercise caution when driving or operating machinery.
Lifestyle Advice
- Engage in regular physical activity.
- Maintain a balanced diet.
- Practice stress-reduction techniques.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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