Sucralose (generic or various brands)
Generic Name
sucralose-12-mg-powder
Manufacturer
Various Manufacturers
Country
Global
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sucralose 12 mg powder | ৳ 2.50 | N/A |
Description
Overview of the medicine
Sucralose is an artificial sweetener derived from sucrose. It is non-caloric as most of it is not broken down or absorbed by the body. It is approximately 600 times sweeter than sugar and is used as a sugar substitute in various foods and beverages.
Uses & Indications
Dosage
Adults
As desired to achieve sweetness, typically one 12 mg sachet per serving, which sweetens like 2 teaspoons of sugar. Acceptable Daily Intake (ADI) is 5 mg/kg body weight/day.
Elderly
Same as adults, within the Acceptable Daily Intake (ADI).
Renal_impairment
No specific dosage adjustment is generally required due to minimal absorption and rapid excretion, but caution advised with very high doses in severe impairment.
How to Take
Oral administration. Dissolve the powder in hot or cold beverages, sprinkle over cereals, fruits, or use in cooking and baking as a sugar substitute.
Mechanism of Action
Sucralose binds strongly to the sweet taste receptors on the tongue, providing a sweet sensation. Unlike sugar, it is not recognized as a carbohydrate by the body and is minimally absorbed, thus providing no calories or affecting blood glucose levels significantly.
Pharmacokinetics
Onset
Immediate (upon contact with taste receptors).
Excretion
The unabsorbed portion is excreted unchanged in feces. The absorbed portion is excreted mainly unchanged in urine.
Half life
Approximately 1.5 to 2.3 hours for the absorbed portion.
Absorption
Poorly absorbed from the gastrointestinal tract (approximately 11-27% of an oral dose).
Metabolism
Minimally metabolized; less than 10% of the absorbed portion is metabolized.
Side Effects
Contraindications
- Known hypersensitivity to sucralose or any excipients in the formulation.
Drug Interactions
General
No significant drug interactions reported due to minimal systemic absorption.
Storage
Store in a cool, dry place, below 30°C (86°F), away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Sucralose has a very high safety margin. Even at very high doses, it is generally well-tolerated. No specific antidote is available; treatment would be symptomatic if any rare reaction occurs.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation within the Acceptable Daily Intake (ADI). Consult a healthcare provider if there are concerns.
Side Effects
Contraindications
- Known hypersensitivity to sucralose or any excipients in the formulation.
Drug Interactions
General
No significant drug interactions reported due to minimal systemic absorption.
Storage
Store in a cool, dry place, below 30°C (86°F), away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Sucralose has a very high safety margin. Even at very high doses, it is generally well-tolerated. No specific antidote is available; treatment would be symptomatic if any rare reaction occurs.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation within the Acceptable Daily Intake (ADI). Consult a healthcare provider if there are concerns.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date when stored properly.
Availability
Pharmacies, Supermarkets, Online Stores
Approval Status
FDA Approved (as food additive/sweetener)
Patent Status
Generally expired, widely available
Clinical Trials
Extensive clinical trials and safety assessments have been conducted on sucralose to support its approval as a food additive and sweetener, demonstrating its safety profile.
Lab Monitoring
- No specific laboratory monitoring is required for sucralose use.
Doctor Notes
- Sucralose is a widely used artificial sweetener generally considered safe for patients, including those with diabetes and pregnant women, when consumed within the Acceptable Daily Intake (ADI).
- Advise patients on appropriate use as a sugar substitute and to report any unusual reactions.
Patient Guidelines
- Use sucralose as a sugar substitute in your daily diet to reduce calorie and sugar intake.
- Do not exceed the Acceptable Daily Intake (ADI) of 5 mg/kg body weight/day.
- If you experience any unusual symptoms or allergic reactions, discontinue use and consult your doctor.
Missed Dose Advice
Not applicable as sucralose is used as needed for sweetening and not for therapeutic dosing.
Driving Precautions
None, sucralose does not impair ability to drive or operate machinery.
Lifestyle Advice
- Sucralose can be a part of a balanced diet for managing weight or blood sugar, but it is not a magic bullet.
- Maintain a healthy lifestyle with regular exercise and a varied diet.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.