Sulbion
Generic Name
Sulbutiamine
Manufacturer
Generic Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sulbion 2 mg syrup | ৳ 23.00 | N/A |
Description
Overview of the medicine
Sulbion 2 mg Syrup contains Sulbutiamine, a synthetic derivative of thiamine (Vitamin B1). It is used to help improve physical and mental fatigue, memory impairment, and certain neurological conditions.
Uses & Indications
Dosage
Adults
Typically 10-20 ml (4-8 mg Sulbutiamine) daily, in divided doses.
Elderly
Similar to adult dosage, or as directed by a physician.
Renal_impairment
No specific dose adjustment generally required, but use with caution in severe cases.
How to Take
To be taken orally, with or without food. Use a measuring spoon or cup for accurate dosing.
Mechanism of Action
Sulbutiamine increases thiamine levels in the brain, which enhances cerebral energy metabolism and improves cholinergic and glutamatergic neurotransmission, contributing to its nootropic and anti-asthenic effects.
Pharmacokinetics
Onset
Effects may be noticed within a few hours of administration.
Excretion
Excreted mainly via the kidneys.
Half life
Plasma half-life is relatively short, typically a few hours.
Absorption
Well absorbed orally due to its lipophilicity.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to Sulbutiamine or any component of the syrup.
Drug Interactions
CNS Stimulants
May potentiate effects of other CNS stimulants.
Thiamine analogues
Potential for additive effects.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture.
Overdose
Overdose is generally well-tolerated. In case of accidental overdose, symptomatic and supportive treatment should be initiated.
Pregnancy & Lactation
Use during pregnancy and lactation should only be done under the strict guidance of a physician, weighing potential benefits against risks.
Side Effects
Contraindications
- Hypersensitivity to Sulbutiamine or any component of the syrup.
Drug Interactions
CNS Stimulants
May potentiate effects of other CNS stimulants.
Thiamine analogues
Potential for additive effects.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture.
Overdose
Overdose is generally well-tolerated. In case of accidental overdose, symptomatic and supportive treatment should be initiated.
Pregnancy & Lactation
Use during pregnancy and lactation should only be done under the strict guidance of a physician, weighing potential benefits against risks.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from manufacturing date.
Availability
Pharmacies
Approval Status
Approved
Patent Status
Off-patent
Clinical Trials
Clinical trials have supported its efficacy in reducing asthenia and improving cognitive functions, particularly memory and attention, in various patient populations.
Lab Monitoring
- Routine lab monitoring is not typically required for Sulbutiamine therapy.
Doctor Notes
- Useful in chronic fatigue syndrome and post-infectious asthenia.
- Advise patients on lifestyle modifications to support recovery.
- Monitor for signs of excitation or sleep disturbances, especially in sensitive individuals.
Patient Guidelines
- Take the medicine exactly as prescribed or directed.
- Do not exceed the recommended dose.
- Store out of reach of children.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Sulbutiamine generally does not affect the ability to drive or operate machinery. However, if you experience dizziness or excitation, avoid such activities.
Lifestyle Advice
- Maintain a balanced diet and adequate rest to support overall well-being.
- Regular exercise may complement the treatment of fatigue.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.