Sulbulin
Generic Name
Sulbulin (as a novel compound)
Manufacturer
HealthMed Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sulbulin 2 mg syrup | ৳ 16.00 | N/A |
Description
Overview of the medicine
Sulbulin 2 mg syrup is an oral medication formulated to relieve coughs by suppressing the cough reflex and thinning thick mucus, making it easier to expel. It is indicated for various respiratory conditions associated with productive and non-productive cough.
Uses & Indications
Dosage
Adults
Adults and adolescents (12 years and above): 5-10 ml (2-4 mg) three times daily, or as directed by physician.
Elderly
No specific dosage adjustment required for elderly, but caution is advised in patients with compromised renal or hepatic function.
Renal_impairment
Use with caution. Dosage reduction may be necessary in severe renal impairment. Consult physician.
How to Take
Take orally with or without food. Use the provided measuring cup or spoon for accurate dosing. Shake the bottle well before each use.
Mechanism of Action
Sulbulin acts as a dual-action agent. It selectively binds to sigma-1 receptors in the brain, modulating the cough reflex center, thereby reducing cough frequency and intensity. Additionally, it has a mucolytic effect by breaking down mucopolysaccharide fibers in bronchial secretions, leading to thinner, less viscous mucus that is easier to clear.
Pharmacokinetics
Onset
Antitussive effect: 30-60 minutes; Mucolytic effect: 1-2 hours.
Excretion
Mainly excreted through urine as metabolites; a small portion is excreted unchanged.
Half life
Approximately 4-6 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract; peak plasma concentrations reached within 1-2 hours.
Metabolism
Primarily metabolized in the liver via CYP450 enzymes.
Side Effects
Contraindications
- •Hypersensitivity to Sulbulin or any component of the formulation.
- •Severe respiratory depression.
- •Acute asthmatic attack.
Drug Interactions
Monoamine Oxidase Inhibitors (MAOIs)
Concurrent use may lead to hypertensive crisis; avoid use within 14 days of MAOI discontinuation.
CNS Depressants (e.g., alcohol, benzodiazepines)
May enhance central nervous system depression, leading to increased sedation.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include nausea, vomiting, dizziness, drowsiness, and in severe cases, respiratory depression. Management is symptomatic and supportive; maintain airway, monitor vital signs. Gastric lavage or activated charcoal may be considered if ingestion is recent.
Pregnancy & Lactation
Pregnancy Category C. Use in pregnant women only if the potential benefit justifies the potential risk to the fetus. Exercise caution when administering to nursing mothers; consult a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Available in pharmacies nationwide
Approval Status
Approved by regulatory authorities
Patent Status
Patent Pending
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Global Brand Names
International brand names for this medicine
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