Sunkist
Generic Name
Ascorbic Acid (Vitamin C)
Manufacturer
Various manufacturers under Sunkist license
Country
USA (origin of Sunkist brand, but manufacturing can be global)
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| sunkist 250 mg chewable tablet | ৳ 1.80 | N/A |
Description
Overview of the medicine
Sunkist 250 mg Chewable Tablet is a vitamin C supplement used to prevent or treat low levels of vitamin C. It acts as an antioxidant and supports immune function.
Uses & Indications
Dosage
Adults
For general supplementation: 250-500 mg daily. For deficiency (scurvy): 250-1000 mg daily in divided doses until saturation.
Elderly
Similar to adult dosage; caution with high doses in individuals with impaired renal function due to increased risk of oxalate stone formation.
Renal_impairment
Use with caution; high doses may increase the risk of oxalate kidney stone formation. Consult a doctor for appropriate dosage adjustments.
How to Take
Chew the tablet thoroughly before swallowing. It can be taken with or without food.
Mechanism of Action
Ascorbic acid is an essential water-soluble vitamin required for collagen formation, tissue repair, and the enzymatic production of certain neurotransmitters. It is a potent antioxidant, protecting cells from oxidative damage, and plays a crucial role in immune system function and iron absorption.
Pharmacokinetics
Onset
Relatively rapid, with peak plasma concentrations reached within 2-3 hours.
Excretion
Excreted primarily by the kidneys, with unmetabolized ascorbic acid and its metabolites appearing in the urine. Renal excretion increases with higher doses.
Half life
Approximately 10-20 days at low body saturation, but much shorter (around 30 minutes) at higher doses due to rapid renal excretion.
Absorption
Readily absorbed from the gastrointestinal tract, primarily in the small intestine, by an active transport mechanism. Absorption is dose-dependent, decreasing with increasing doses.
Metabolism
Partially metabolized in the liver to inactive metabolites, primarily dehydroascorbic acid and then further to 2,3-diketogulonic acid and oxalate.
Side Effects
Contraindications
- Hypersensitivity to ascorbic acid or any component of the formulation
- Hemochromatosis or other conditions with increased iron overload (high doses of Vitamin C can increase iron absorption)
Drug Interactions
Warfarin
Very high doses of Vitamin C might theoretically interfere with anticoagulant therapy, although clinical significance for 250mg is low.
Deferoxamine
Concurrent use may enhance iron toxicity, especially for cardiac effects. Avoid combination.
Oral Contraceptives
May lead to lower plasma levels of ascorbic acid.
Aluminium-containing Antacids
Ascorbic acid can increase the absorption of aluminum from antacids, especially in patients with renal impairment.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is generally non-toxic. High doses (over 2000 mg/day) may cause gastrointestinal disturbances (e.g., diarrhea, nausea, abdominal cramps) and increase the risk of oxalate kidney stone formation in susceptible individuals. Management is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation at recommended daily allowances. For high doses, consult a healthcare provider.
Side Effects
Contraindications
- Hypersensitivity to ascorbic acid or any component of the formulation
- Hemochromatosis or other conditions with increased iron overload (high doses of Vitamin C can increase iron absorption)
Drug Interactions
Warfarin
Very high doses of Vitamin C might theoretically interfere with anticoagulant therapy, although clinical significance for 250mg is low.
Deferoxamine
Concurrent use may enhance iron toxicity, especially for cardiac effects. Avoid combination.
Oral Contraceptives
May lead to lower plasma levels of ascorbic acid.
Aluminium-containing Antacids
Ascorbic acid can increase the absorption of aluminum from antacids, especially in patients with renal impairment.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Acute overdose is generally non-toxic. High doses (over 2000 mg/day) may cause gastrointestinal disturbances (e.g., diarrhea, nausea, abdominal cramps) and increase the risk of oxalate kidney stone formation in susceptible individuals. Management is symptomatic and supportive.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation at recommended daily allowances. For high doses, consult a healthcare provider.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from the date of manufacture, depending on storage conditions.
Availability
Pharmacies, supermarkets, online stores
Approval Status
Approved by major regulatory bodies globally
Patent Status
Generic
WHO Essential Medicine
YesClinical Trials
Numerous clinical trials and studies have validated the efficacy and safety of ascorbic acid for vitamin C deficiency, immune support, and as an antioxidant. Specific brand-related trials are less common for basic vitamin supplements.
Lab Monitoring
- Generally not required for typical supplementation doses.
- In cases of suspected severe deficiency or very high dose therapy, plasma ascorbic acid levels may be monitored.
- For individuals prone to kidney stones taking high doses, urine oxalate levels might be considered.
Doctor Notes
- Advise patients that vitamin C is best obtained through a balanced diet.
- Caution patients with a history of kidney stones or renal impairment regarding high-dose vitamin C intake.
- Inform patients about potential mild GI side effects at higher doses.
Patient Guidelines
- Chew the tablet thoroughly before swallowing.
- Do not exceed the recommended dose without consulting a healthcare professional.
- Inform your doctor about all other medications and supplements you are taking.
- Store medicine out of reach of children.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Sunkist 250 mg Chewable Tablet is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in fruits and vegetables to ensure adequate nutrient intake.
- Stay hydrated by drinking plenty of water throughout the day.
- Engage in regular physical activity for overall health benefits.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.