Suvo
Generic Name
Escitalopram
Manufacturer
Acme Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| suvo 10 mg tablet | ৳ 35.00 | ৳ 350.00 |
Description
Overview of the medicine
Suvo 10 mg Tablet contains Escitalopram, a selective serotonin reuptake inhibitor (SSRI) used to treat major depressive disorder and generalized anxiety disorder. It helps to improve mood and feelings of well-being.
Uses & Indications
Dosage
Adults
Initial dose is 10 mg once daily, may be increased to a maximum of 20 mg daily after at least one week.
Elderly
A lower initial dose (e.g., 5 mg once daily) may be considered, maximum 10 mg daily.
Renal_impairment
No dosage adjustment generally needed for mild to moderate impairment; caution in severe impairment.
How to Take
Take orally once daily, with or without food. Swallow the tablet whole with water.
Mechanism of Action
Escitalopram selectively inhibits the reuptake of serotonin (5-HT) in the brain, thereby increasing the concentration of serotonin in the synaptic cleft. This leads to enhanced serotonergic neurotransmission.
Pharmacokinetics
Onset
Initial antidepressant effects may be seen within 1-2 weeks, full effect within 4-6 weeks.
Excretion
Excreted primarily via urine, with some fecal excretion.
Half life
Approximately 27-32 hours.
Absorption
Well absorbed from the gastrointestinal tract, not significantly affected by food.
Metabolism
Extensively metabolized in the liver by CYP3A4, CYP2C19, and CYP2D6 to inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to escitalopram or any component of the formulation.
- Concomitant use with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of discontinuing an MAOI.
- Concomitant use with pimozide.
Drug Interactions
MAOIs
Increased risk of serotonin syndrome.
Pimozide
Contraindicated due to QT prolongation risk.
Warfarin
May alter anticoagulant effects; monitor INR.
NSAIDs/Aspirin
Increased risk of gastrointestinal bleeding.
Serotonergic drugs (e.g., triptans, tramadol, other SSRIs, SNRIs)
Increased risk of serotonin syndrome.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include dizziness, tremor, agitation, somnolence, nausea, vomiting, tachycardia, and rarely, seizures or serotonin syndrome. Treatment is symptomatic and supportive. Maintain an open airway, monitor cardiac and vital signs. Activated charcoal may be considered. There is no specific antidote.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Neonates exposed to SSRIs late in the third trimester have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding. Escitalopram is excreted in human milk; use with caution in breastfeeding mothers.
Side Effects
Contraindications
- Hypersensitivity to escitalopram or any component of the formulation.
- Concomitant use with Monoamine Oxidase Inhibitors (MAOIs) or within 14 days of discontinuing an MAOI.
- Concomitant use with pimozide.
Drug Interactions
MAOIs
Increased risk of serotonin syndrome.
Pimozide
Contraindicated due to QT prolongation risk.
Warfarin
May alter anticoagulant effects; monitor INR.
NSAIDs/Aspirin
Increased risk of gastrointestinal bleeding.
Serotonergic drugs (e.g., triptans, tramadol, other SSRIs, SNRIs)
Increased risk of serotonin syndrome.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include dizziness, tremor, agitation, somnolence, nausea, vomiting, tachycardia, and rarely, seizures or serotonin syndrome. Treatment is symptomatic and supportive. Maintain an open airway, monitor cardiac and vital signs. Activated charcoal may be considered. There is no specific antidote.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Neonates exposed to SSRIs late in the third trimester have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding. Escitalopram is excreted in human milk; use with caution in breastfeeding mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 to 36 months from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Escitalopram has undergone extensive clinical trials demonstrating its efficacy and safety in the treatment of major depressive disorder, generalized anxiety disorder, and other anxiety disorders. Trials have consistently shown superiority over placebo and comparable efficacy to other SSRIs.
Lab Monitoring
- No routine lab monitoring required. Consider monitoring serum sodium in patients at risk for hyponatremia. Liver and renal function tests if clinically indicated or with comorbidities.
Doctor Notes
- Educate patients on potential delayed onset of action and importance of adherence.
- Monitor for signs of suicidality, especially during initial therapy and dose changes.
- Consider gradual tapering when discontinuing to minimize withdrawal symptoms.
Patient Guidelines
- Take the medicine regularly as prescribed, do not stop abruptly without consulting your doctor.
- It may take several weeks to feel the full benefits, so be patient.
- Report any new or worsening symptoms, especially changes in mood or suicidal thoughts, to your doctor immediately.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
This medicine may cause dizziness, drowsiness, or visual disturbances. Avoid driving or operating machinery until you know how it affects you.
Lifestyle Advice
- Incorporate regular exercise and a balanced diet into your routine.
- Practice stress-reduction techniques like meditation or yoga.
- Maintain good sleep hygiene.
- Avoid alcohol while on this medication.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.