Suvotol
Generic Name
Suvotol 10 mg Tablet
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| suvotol 10 mg tablet | ৳ 25.00 | ৳ 250.00 |
Description
Overview of the medicine
Suvotol 10 mg Tablet contains Suvotol, a selective beta-1 adrenergic receptor blocker, used to treat hypertension, angina pectoris, and certain cardiac arrhythmias. It helps to lower blood pressure and reduce the heart's workload.
Uses & Indications
Dosage
Adults
Initially 10 mg once daily, may be increased to 20 mg once daily after 1-2 weeks if necessary. Maximum 40 mg daily.
Elderly
Lower initial dose, e.g., 5 mg once daily, with gradual titration based on response and tolerability.
Renal_impairment
Dose adjustment required. For CrCl < 35 mL/min, reduce dose by 50% or extend dosing interval.
How to Take
Take orally once daily, preferably at the same time each day. Can be taken with or without food. Do not crush or chew the tablet.
Mechanism of Action
Suvotol selectively blocks beta-1 adrenergic receptors, primarily in the heart. This reduces heart rate, myocardial contractility, and cardiac output, leading to a decrease in blood pressure. It also reduces renin release from the kidneys.
Pharmacokinetics
Onset
Within 1-2 hours
Excretion
Mainly renal excretion, both as unchanged drug and metabolites.
Half life
Approximately 6-9 hours
Absorption
Well absorbed from the gastrointestinal tract, with bioavailability around 50-60% due to first-pass metabolism.
Metabolism
Primarily hepatic metabolism, with some active metabolites.
Side Effects
Contraindications
- Severe bradycardia (heart rate < 50 bpm)
- Second or third-degree atrioventricular (AV) block
- Decompensated heart failure
- Cardiogenic shock
- Sick sinus syndrome
Drug Interactions
Clonidine
Risk of rebound hypertension if clonidine is withdrawn abruptly while taking Suvotol.
Digitalis Glycosides
Increased risk of bradycardia and AV block.
NSAIDs (e.g., Ibuprofen)
May reduce the antihypertensive effect of Suvotol.
Calcium Channel Blockers (e.g., Verapamil, Diltiazem)
Increased risk of bradycardia and hypotension. Monitor heart rate and blood pressure.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms include severe bradycardia, hypotension, acute heart failure, and bronchospasm. Management involves supportive measures, gastric lavage, activated charcoal, and intravenous atropine for bradycardia, glucagon for hypotension, and inotropes for heart failure.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs the risk to the fetus. Small amounts may pass into breast milk; use with caution during lactation. Consult a doctor.
Side Effects
Contraindications
- Severe bradycardia (heart rate < 50 bpm)
- Second or third-degree atrioventricular (AV) block
- Decompensated heart failure
- Cardiogenic shock
- Sick sinus syndrome
Drug Interactions
Clonidine
Risk of rebound hypertension if clonidine is withdrawn abruptly while taking Suvotol.
Digitalis Glycosides
Increased risk of bradycardia and AV block.
NSAIDs (e.g., Ibuprofen)
May reduce the antihypertensive effect of Suvotol.
Calcium Channel Blockers (e.g., Verapamil, Diltiazem)
Increased risk of bradycardia and hypotension. Monitor heart rate and blood pressure.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms include severe bradycardia, hypotension, acute heart failure, and bronchospasm. Management involves supportive measures, gastric lavage, activated charcoal, and intravenous atropine for bradycardia, glucagon for hypotension, and inotropes for heart failure.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs the risk to the fetus. Small amounts may pass into breast milk; use with caution during lactation. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Available in pharmacies nationwide
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Generic available, Patent expired
WHO Essential Medicine
YesClinical Trials
Several clinical trials have demonstrated the efficacy and safety of Suvotol in the management of hypertension and angina pectoris. Ongoing post-market surveillance studies are evaluating long-term outcomes.
Lab Monitoring
- Blood pressure monitoring
- Heart rate monitoring
- Renal function (BUN, creatinine) in patients with kidney impairment
Doctor Notes
- Counsel patients on the importance of gradual withdrawal to avoid rebound effects.
- Monitor for signs of heart failure and bradycardia, especially in elderly patients.
- Consider renal dose adjustment for patients with impaired kidney function.
Patient Guidelines
- Take Suvotol regularly as prescribed, even if you feel well.
- Do not stop taking the medicine suddenly without consulting your doctor.
- Report any unusual side effects to your doctor.
- Avoid driving or operating machinery until you know how this medicine affects you, due to potential dizziness.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
May cause dizziness or fatigue, especially at the start of treatment or when the dose is increased. Patients should exercise caution when driving or operating machinery until they are sure the medicine does not adversely affect their ability.
Lifestyle Advice
- Adopt a healthy diet low in sodium and saturated fats.
- Engage in regular physical activity as advised by your doctor.
- Maintain a healthy weight.
- Limit alcohol consumption and avoid smoking.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.