Syalox-Plus
Generic Name
Sodium Hyaluronate + Chondroitin Sulfate
Manufacturer
Fidia Farmaceutici S.p.A.
Country
Italy
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| syalox plus 300 mg tablet | ৳ 80.00 | N/A |
Description
Overview of the medicine
Syalox-Plus 300 mg Tablet is a medical device or nutritional supplement containing high molecular weight Hyaluronic Acid and Chondroitin Sulfate. It is designed to support joint health, improve joint lubrication, and reduce pain and stiffness associated with osteoarthritis by restoring the viscoelastic properties of synovial fluid and protecting cartilage.
Uses & Indications
Dosage
Adults
One tablet daily, preferably with a meal, or as directed by a healthcare professional.
Elderly
No specific dose adjustment generally required, follow adult dosage.
Renal_impairment
No specific dose adjustment mentioned, consult a healthcare professional.
How to Take
Take orally with a glass of water, preferably during or after meals to enhance absorption and minimize gastrointestinal upset.
Mechanism of Action
Hyaluronic Acid (HA) acts as a viscosupplement, restoring the viscoelasticity of the synovial fluid, which lubricates joints and absorbs shock. Chondroitin Sulfate (CS) is a key component of cartilage, helping to maintain its structural integrity and resistance to compression, potentially inhibiting cartilage-degrading enzymes and promoting cartilage repair. The combination provides synergistic support for joint health.
Pharmacokinetics
Onset
Effects on joint symptoms are typically observed over several weeks to months of continuous use.
Excretion
Primarily renal excretion of metabolites.
Half life
HA's systemic half-life is short (minutes to hours), but its residence time in joints can be longer. CS has a half-life of around 5-15 hours.
Absorption
Oral HA and CS are absorbed, though bioavailability can vary. HA is typically broken down in the gut and absorbed as smaller fragments. CS is absorbed in the gastrointestinal tract.
Metabolism
HA is metabolized in the liver and local tissues by hyaluronidases. CS is metabolized in the liver.
Side Effects
Contraindications
- •Hypersensitivity to Hyaluronic Acid, Chondroitin Sulfate, or any excipients in the formulation
- •Children below 12 years (unless specifically advised by a doctor)
Drug Interactions
Anticoagulants (e.g., Warfarin)
Chondroitin Sulfate may have mild anticoagulant effects, potentially enhancing the effects of anticoagulant medications. Monitor INR if co-administered.
Storage
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely to cause severe toxicity. In case of accidental overdose, symptomatic and supportive measures should be taken.
Pregnancy & Lactation
Limited data on use during pregnancy and lactation. It is advisable to consult a healthcare professional before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date.
Availability
Pharmacies, drugstores, online retailers
Approval Status
Marketed as a medical device / food supplement
Patent Status
Proprietary formulation, active ingredients generally off-patent
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Global Brand Names
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