Tamsulin Plus
Generic Name
Tamsulosin Hydrochloride
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tamsulin plus 04 mg capsule | ৳ 18.00 | ৳ 72.00 |
Description
Overview of the medicine
Tamsulosin is an alpha1-adrenoceptor antagonist used for benign prostatic hyperplasia (BPH) to improve urine flow and reduce symptoms.
Uses & Indications
Dosage
Adults
0.4 mg once daily, taken approximately 30 minutes after the same meal each day.
Elderly
No dosage adjustment is generally required.
Renal_impairment
No dosage adjustment is generally required for mild to moderate impairment. Use with caution in severe impairment.
How to Take
Orally, once daily after a meal. Swallow whole; do not crush, chew, or open the capsule.
Mechanism of Action
Selectively blocks alpha1A and alpha1D adrenoceptors in the prostate, bladder neck, and urethra, leading to relaxation of smooth muscle and improved urine flow.
Pharmacokinetics
Onset
Symptom improvement typically within 2-4 weeks.
Excretion
Primarily excreted in the urine as metabolites, with less than 10% excreted unchanged.
Half life
Approximately 9-15 hours.
Absorption
Well absorbed from the gastrointestinal tract. Food can reduce absorption.
Metabolism
Extensively metabolized in the liver, primarily by CYP3A4 and CYP2D6.
Side Effects
Contraindications
- Hypersensitivity to tamsulosin or any component of the formulation.
- History of orthostatic hypotension.
- Severe hepatic impairment.
Drug Interactions
PDE5 inhibitors
Increased risk of hypotension.
Other alpha-blockers
Potentiated hypotensive effects.
Strong CYP3A4 inhibitors (e.g., ketoconazole)
Increase tamsulosin exposure.
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
Symptomatic and supportive treatment for hypotension.
Pregnancy & Lactation
Not indicated for use in women.
Side Effects
Contraindications
- Hypersensitivity to tamsulosin or any component of the formulation.
- History of orthostatic hypotension.
- Severe hepatic impairment.
Drug Interactions
PDE5 inhibitors
Increased risk of hypotension.
Other alpha-blockers
Potentiated hypotensive effects.
Strong CYP3A4 inhibitors (e.g., ketoconazole)
Increase tamsulosin exposure.
Storage
Store below 30°C in a dry place, away from light and moisture.
Overdose
Symptomatic and supportive treatment for hypotension.
Pregnancy & Lactation
Not indicated for use in women.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Generics available
Clinical Trials
Extensive clinical trials have demonstrated efficacy and safety in BPH patients.
Lab Monitoring
- Regular blood pressure monitoring.
- Liver and kidney function tests (if clinically indicated).
Doctor Notes
- Counsel patients about orthostatic hypotension and IFIS risk.
- Consider alternative treatment if severe orthostatic symptoms occur.
Patient Guidelines
- Take as directed by your doctor.
- Do not crush or chew the capsule.
- Report any dizziness or fainting to your doctor.
Missed Dose Advice
Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
Driving Precautions
May cause dizziness or lightheadedness, especially at the start of treatment. Patients should be warned about driving or operating machinery.
Lifestyle Advice
- Maintain a healthy diet and regular exercise.
- Avoid sudden changes in posture to minimize dizziness.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.