Tapisis
Generic Name
Tapinarof 1% Cream
Manufacturer
Dermavant Sciences
Country
United States
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tapisis 1 cream | ৳ 1,000.00 | N/A |
Description
Overview of the medicine
Tapisis-1-Cream (Tapinarof 1% Cream) is a topical medication used for the treatment of plaque psoriasis in adults. It works by targeting the aryl hydrocarbon receptor (AhR) to reduce inflammation and normalize skin cell growth.
Uses & Indications
Dosage
Adults
Apply a thin layer to affected areas once daily. Wash hands after application.
Elderly
No specific dose adjustment required.
Renal_impairment
No specific dose adjustment required as systemic absorption is minimal.
How to Take
For topical use only. Apply to affected skin areas. Avoid application to eyes, mouth, or vagina. Do not wrap or bandage the treated area unless directed by a doctor.
Mechanism of Action
Tapinarof is an aryl hydrocarbon receptor (AhR) agonist. Activation of AhR regulates various cellular processes, including inflammation and skin barrier function. In psoriasis, AhR activation by tapinarof helps to reduce pro-inflammatory cytokines, decrease epidermal proliferation, and promote skin barrier restoration.
Pharmacokinetics
Onset
Clinical improvement typically seen within 4-8 weeks.
Excretion
Primarily fecal, with some renal excretion.
Half life
Approximately 18.9 hours (plasma).
Absorption
Systemic absorption is minimal following topical application.
Metabolism
Extensively metabolized primarily via oxidation and glucuronidation.
Side Effects
Contraindications
- •Hypersensitivity to tapinarof or any component of the cream.
Drug Interactions
Storage
Store at room temperature (20°C to 25°C). Do not freeze. Keep out of reach of children. Keep the tube tightly closed.
Overdose
Overdose with topical application is unlikely due to minimal systemic absorption. In case of accidental ingestion, seek medical advice.
Pregnancy & Lactation
Use in pregnancy only if potential benefit justifies potential risk to the fetus. Caution advised during lactation; systemic absorption is minimal, but risks to nursing infant are unknown.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Refer to product label for specific shelf life (typically 24 months from manufacturing).
Availability
Pharmacies
Approval Status
FDA Approved
Patent Status
Patented (currently under patent protection)
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine
More Medicines
Explore other medicines you might be interested in