Telabee
Generic Name
Telmisartan
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| telabee 25 mg tablet | ৳ 130.00 | ৳ 1,300.00 |
Description
Overview of the medicine
Telmisartan is an angiotensin II receptor blocker (ARB) used to treat high blood pressure (hypertension) and to reduce the risk of cardiovascular events in certain high-risk patients. It works by relaxing blood vessels, allowing blood to flow more easily.
Uses & Indications
Dosage
Adults
Usually 40 mg once daily. May be increased to a maximum of 80 mg once daily.
Elderly
No dosage adjustment necessary.
Renal_impairment
No dosage adjustment necessary for mild to moderate impairment. Not recommended for severe impairment or hemodialysis.
How to Take
Oral administration, once daily with or without food.
Mechanism of Action
Telmisartan selectively blocks the binding of angiotensin II to the AT1 receptor in various tissues, including vascular smooth muscle and the adrenal gland. This inhibits the vasoconstrictor and aldosterone-secreting effects of angiotensin II, leading to vasodilation and reduced blood pressure.
Pharmacokinetics
Onset
3 hours
Excretion
Primarily excreted unchanged in faeces (over 97%).
Half life
Approximately 24 hours
Absorption
Rapidly absorbed from the gastrointestinal tract. Absolute bioavailability is dose-dependent, approx. 42% for 40 mg and 58% for 160 mg.
Metabolism
Minimally metabolized by conjugation to form an acylglucuronide; no cytochrome P450 involvement.
Side Effects
Contraindications
- Hypersensitivity to the active substance or to any of the excipients
- Second and third trimesters of pregnancy
- Biliary obstructive disorders
- Severe hepatic impairment
- Concomitant use with aliskiren in patients with diabetes or renal impairment
Drug Interactions
NSAIDs
May reduce the antihypertensive effect of telmisartan and increase the risk of renal function deterioration.
Digoxin
Increased plasma digoxin levels.
Lithium
Increased serum lithium concentrations and toxicity have been reported.
Diuretics
Increased risk of hypotension and renal impairment.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms: Hypotension, dizziness, tachycardia, bradycardia. Management: Symptomatic and supportive treatment. Hemodialysis is not effective.
Pregnancy & Lactation
Contraindicated in the second and third trimesters of pregnancy due to fetal toxicity. Not recommended during the first trimester. Breastfeeding is not recommended.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months
Availability
Pharmacies, hospitals, clinics
Approval Status
Approved by FDA and DGDA
Patent Status
Generic available
Clinical Trials
Numerous clinical trials have demonstrated Telmisartan's efficacy in hypertension and cardiovascular risk reduction, notably the ONTARGET and TRANSCEND trials.
Lab Monitoring
- Renal function (creatinine, BUN)
- Serum electrolytes (potassium)
Doctor Notes
- Monitor blood pressure and renal function regularly.
- Advise patients on lifestyle modifications.
- Caution in patients with bilateral renal artery stenosis.
Patient Guidelines
- Take medicine at the same time each day.
- Do not stop taking the medicine without consulting your doctor.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If a dose is missed, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
May cause dizziness or drowsiness, which could impair driving or operating machinery. Exercise caution until you know how Telmisartan affects you.
Lifestyle Advice
- Maintain a healthy diet low in sodium.
- Engage in regular physical activity.
- Avoid smoking and excessive alcohol consumption.
- Monitor blood pressure regularly.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.