Terfun
Generic Name
Terbinafine 1% Cream
Manufacturer
Reputable Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| terfun 1 cream | ৳ 75.00 | N/A |
Description
Overview of the medicine
Terfun 1% Cream contains Terbinafine, an antifungal agent used to treat various fungal skin infections such as ringworm, athlete's foot, and jock itch. It works by killing the fungi that cause these infections.
Uses & Indications
Dosage
Adults
Apply to the affected area once or twice daily for 1 to 2 weeks, depending on the infection type. Continue for a few days after symptoms clear.
Elderly
No specific dosage adjustment is necessary for elderly patients.
Renal_impairment
No dosage adjustment required as systemic absorption is minimal.
How to Take
For topical use only. Clean and dry the affected area thoroughly before applying a thin layer of cream. Gently rub it in. Wash hands immediately after application.
Mechanism of Action
Terbinafine inhibits squalene epoxidase, a key enzyme in fungal sterol biosynthesis. This leads to an accumulation of squalene within the fungal cell and a deficiency of ergosterol, resulting in fungal cell death.
Pharmacokinetics
Onset
Clinical improvement usually begins within a few days of treatment.
Excretion
Not significantly excreted systemically due to minimal absorption.
Half life
Not relevant for topical application due to minimal systemic absorption.
Absorption
When applied topically, less than 5% of the dose is absorbed, resulting in very low systemic exposure.
Metabolism
Minimal systemic metabolism due to low absorption.
Side Effects
Contraindications
- Hypersensitivity to terbinafine or any of the excipients.
- Not for ophthalmic, oral, or intravaginal use.
Drug Interactions
Systemic Medications
Minimal systemic absorption means topical terbinafine is unlikely to cause clinically significant drug interactions with systemically administered medications.
Storage
Store in a cool and dry place, below 30°C. Protect from light. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic toxicity due to poor absorption. If applied excessively, wipe off the excess cream and wash the area. In case of accidental ingestion, seek medical advice.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the potential benefits outweigh the potential risks. Caution should be exercised when administered to a nursing woman, consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to terbinafine or any of the excipients.
- Not for ophthalmic, oral, or intravaginal use.
Drug Interactions
Systemic Medications
Minimal systemic absorption means topical terbinafine is unlikely to cause clinically significant drug interactions with systemically administered medications.
Storage
Store in a cool and dry place, below 30°C. Protect from light. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic toxicity due to poor absorption. If applied excessively, wipe off the excess cream and wash the area. In case of accidental ingestion, seek medical advice.
Pregnancy & Lactation
Use during pregnancy only if clearly needed and the potential benefits outweigh the potential risks. Caution should be exercised when administered to a nursing woman, consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies, Drugstores
Approval Status
Approved (Generic)
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Terbinafine 1% cream has been widely studied and proven effective in numerous clinical trials for its indicated uses.
Lab Monitoring
- No specific lab monitoring required for topical Terbinafine.
Doctor Notes
- Advise patients on proper hygiene to prevent recurrence.
- Emphasize completion of the full treatment course.
- Monitor for signs of allergic reactions or worsening of infection.
Patient Guidelines
- Complete the full course of treatment, even if symptoms improve.
- Keep the affected area clean and dry.
- Avoid sharing towels, clothing, and footwear to prevent spreading the infection.
- Wash hands thoroughly after applying the cream.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply extra cream to make up for a missed dose.
Driving Precautions
Terfun 1% Cream has no known effects on the ability to drive or operate machinery.
Lifestyle Advice
- Wear loose-fitting, breathable clothing.
- Avoid tight, synthetic fabrics.
- Change socks daily for foot infections.
- Maintain good personal hygiene.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.