Teslarin
Generic Name
teslar-20-mg-tablet
Manufacturer
Globex Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| teslar 20 mg tablet | ৳ 7.00 | ৳ 49.00 |
Description
Overview of the medicine
Teslar 20 mg tablet is a novel analgesic and anti-inflammatory medication used for the symptomatic relief of mild to moderate pain and inflammation associated with various musculoskeletal conditions.
Uses & Indications
Dosage
Adults
Oral: 20 mg once or twice daily, or as directed by the physician. Maximum daily dose should not exceed 40 mg.
Elderly
No specific dose adjustment is generally required, but caution is advised due to potential age-related decrease in renal function. Start with the lowest effective dose.
Renal_impairment
For mild to moderate renal impairment, a dose reduction to 20 mg once daily may be considered. Not recommended in severe renal impairment (CrCl <30 mL/min).
How to Take
Take the tablet orally, with or without food. To minimize gastrointestinal upset, it is generally recommended to take with food or milk.
Mechanism of Action
Teslar acts as a selective inhibitor of cyclooxygenase, primarily targeting COX-2. This inhibition reduces the synthesis of prostaglandins, which are key mediators of pain and inflammation, thereby exerting its analgesic and anti-inflammatory effects.
Pharmacokinetics
Onset
Analgesic effect observed within 30-60 minutes.
Excretion
Mainly excreted via urine (approximately 70%) and feces (approximately 30%) as metabolites.
Half life
Plasma elimination half-life is approximately 6-8 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract, achieving peak plasma concentrations within 1-2 hours.
Metabolism
Extensively metabolized in the liver, primarily via CYP2C9 and CYP3A4 enzymes.
Side Effects
Contraindications
- Hypersensitivity to Teslar or any excipients
- History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Active gastrointestinal ulceration or bleeding
- Severe renal or hepatic impairment
- Severe heart failure
- Third trimester of pregnancy
Drug Interactions
Lithium
May increase plasma lithium levels, leading to toxicity.
Methotrexate
May increase methotrexate toxicity.
Corticosteroids
Increased risk of gastrointestinal ulceration or bleeding.
Diuretics and ACE inhibitors
May reduce the antihypertensive effect and increase the risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, nausea, vomiting, epigastric pain, lethargy, and gastrointestinal bleeding. Management involves symptomatic and supportive treatment. Gastric lavage or activated charcoal may be considered within an hour of ingestion.
Pregnancy & Lactation
Pregnancy Category C (first and second trimesters), Category D (third trimester). Use during pregnancy should be avoided unless the potential benefit outweighs the risk. Not recommended during breastfeeding as it may pass into breast milk.
Side Effects
Contraindications
- Hypersensitivity to Teslar or any excipients
- History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Active gastrointestinal ulceration or bleeding
- Severe renal or hepatic impairment
- Severe heart failure
- Third trimester of pregnancy
Drug Interactions
Lithium
May increase plasma lithium levels, leading to toxicity.
Methotrexate
May increase methotrexate toxicity.
Corticosteroids
Increased risk of gastrointestinal ulceration or bleeding.
Diuretics and ACE inhibitors
May reduce the antihypertensive effect and increase the risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose may include drowsiness, nausea, vomiting, epigastric pain, lethargy, and gastrointestinal bleeding. Management involves symptomatic and supportive treatment. Gastric lavage or activated charcoal may be considered within an hour of ingestion.
Pregnancy & Lactation
Pregnancy Category C (first and second trimesters), Category D (third trimester). Use during pregnancy should be avoided unless the potential benefit outweighs the risk. Not recommended during breastfeeding as it may pass into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Under patent
Clinical Trials
Teslar has undergone extensive Phase I, II, and III clinical trials demonstrating its efficacy and safety profile for various pain and inflammatory conditions. Post-marketing surveillance is ongoing to monitor long-term outcomes.
Lab Monitoring
- Regular monitoring of renal function (serum creatinine, BUN) is recommended, especially in elderly patients or those with pre-existing renal impairment.
- Liver function tests (ALT, AST) should be performed periodically during long-term therapy.
- Complete blood count (CBC) should be monitored, especially in patients receiving long-term treatment.
Doctor Notes
- Assess cardiovascular risk factors before prescribing Teslar, especially for long-term use.
- Monitor renal function, liver function, and blood pressure regularly in patients on chronic therapy.
- Advise patients on signs and symptoms of GI bleeding and cardiovascular events.
Patient Guidelines
- Take Teslar exactly as prescribed by your doctor and do not exceed the recommended dose.
- Report any unusual bleeding, black or tarry stools, or severe abdominal pain immediately to your doctor.
- Do not take Teslar with other NSAIDs (e.g., ibuprofen, naproxen) without consulting your doctor.
- Inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Teslar may cause dizziness or visual disturbances in some patients. If you experience these effects, avoid driving or operating machinery.
Lifestyle Advice
- Avoid excessive alcohol consumption while taking Teslar to reduce the risk of gastrointestinal side effects.
- Maintain adequate hydration, especially during hot weather or exercise.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.