Testoren
Generic Name
Testosterone Enanthate 250 mg Injection
Manufacturer
Generic Pharma Co.
Country
Global (often manufactured in various countries)
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| testoren 250 mg injection | ৳ 174.00 | N/A |
Description
Overview of the medicine
Testosterone Enanthate injection is an androgen used for testosterone replacement therapy in males with conditions associated with deficient or absent endogenous testosterone. It is administered intramuscularly.
Uses & Indications
Dosage
Adults
Typically 50-400 mg every 2 to 4 weeks, administered intramuscularly. Dosage should be individualized based on clinical response and serum testosterone levels.
Elderly
Lower doses may be considered, and careful monitoring for adverse effects, especially cardiovascular and prostate-related, is required.
Renal_impairment
No specific dosage adjustment guidelines, but caution is advised due to potential fluid retention.
How to Take
For intramuscular injection only, preferably into the gluteal muscle. Must not be administered intravenously.
Mechanism of Action
Testosterone is an endogenous androgen, responsible for the normal growth and development of male sex organs and for maintenance of secondary sex characteristics. It acts by binding to androgen receptors, leading to gene expression changes.
Pharmacokinetics
Onset
Therapeutic effects typically observed within weeks, peak levels within days post-injection.
Excretion
Mainly via urine as metabolites; some excreted in feces.
Half life
Approximately 4.5 days for testosterone enanthate (ester hydrolysis to testosterone, then testosterone half-life is minutes).
Absorption
Slowly absorbed from the intramuscular injection site. Testosterone enanthate is a long-acting ester of testosterone.
Metabolism
Primarily hepatic, converted to active and inactive metabolites (e.g., dihydrotestosterone, estradiol).
Side Effects
Contraindications
- •Known hypersensitivity to testosterone or any component
- •Men with breast cancer or known or suspected prostate cancer
- •Pregnancy or breastfeeding (women)
- •Severe cardiac, renal, or hepatic disease
- •Hypercalcemia associated with malignancy
Drug Interactions
Insulin
Testosterone may decrease blood glucose, potentially requiring insulin dose adjustment in diabetics.
Corticosteroids
Increased risk of fluid retention and edema.
Thyroid hormones
Testosterone may decrease thyroxine-binding globulin, leading to decreased total T4 and T3 levels (free levels usually unchanged).
Anticoagulants (e.g., Warfarin)
May increase anticoagulant effects, requiring dose adjustment of warfarin and close monitoring of INR.
Storage
Store at controlled room temperature (20-25°C), away from light. Do not refrigerate or freeze.
Overdose
Symptoms of overdose include irritability, nervousness, weight gain, and prolonged erections. Treatment is symptomatic and supportive; discontinue treatment and resume at a lower dose after symptoms resolve.
Pregnancy & Lactation
Contraindicated in pregnant or breastfeeding women due to potential virilization of the fetus/infant. Category X for pregnancy.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years when stored properly.
Availability
Hospitals, pharmacies
Approval Status
Approved by major regulatory bodies (e.g., FDA, DGDA)
Patent Status
Generic available, original patent expired
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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