tetramycin
Generic Name
tetracycline hydrochloride
Manufacturer
Generic Pharma Inc.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tetramycin 250 mg capsule | ৳ 1.30 | ৳ 13.00 |
Description
Overview of the medicine
Tetracycline is a broad-spectrum antibiotic used to treat bacterial infections. It works by inhibiting bacterial protein synthesis.
Uses & Indications
Dosage
Adults
250 mg to 500 mg every 6 hours, orally.
Elderly
No specific dose adjustment for elderly unless renal impairment exists.
Renal_impairment
Dose reduction necessary, consult physician. Avoid if severe impairment.
How to Take
Take orally with a full glass of water, preferably on an empty stomach, at least 1 hour before or 2 hours after meals. Avoid taking with milk or dairy products.
Mechanism of Action
Binds to the 30S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis.
Pharmacokinetics
Onset
Typically within 1-2 hours.
Excretion
Primarily via kidneys (glomerular filtration) and bile/feces.
Half life
Approximately 6-11 hours.
Absorption
Incomplete and variable oral absorption, reduced by food and dairy products.
Metabolism
Partially metabolized in the liver.
Side Effects
Contraindications
- Known hypersensitivity to tetracyclines
- Pregnancy (especially second and third trimesters)
- Lactation
- Children under 8 years of age
- Severe renal impairment
Drug Interactions
Warfarin
Potentiates anticoagulant effect.
Iron preparations
Reduced absorption of tetracycline.
Oral contraceptives
May reduce efficacy of oral contraceptives.
Antacids (aluminum, calcium, magnesium)
Reduced absorption of tetracycline.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
No specific antidote. Treatment is supportive and symptomatic, including gastric lavage or induced emesis if recent ingestion.
Pregnancy & Lactation
Contraindicated during pregnancy (especially after 4th month due to tooth discoloration in fetus) and lactation (excreted in breast milk).
Side Effects
Contraindications
- Known hypersensitivity to tetracyclines
- Pregnancy (especially second and third trimesters)
- Lactation
- Children under 8 years of age
- Severe renal impairment
Drug Interactions
Warfarin
Potentiates anticoagulant effect.
Iron preparations
Reduced absorption of tetracycline.
Oral contraceptives
May reduce efficacy of oral contraceptives.
Antacids (aluminum, calcium, magnesium)
Reduced absorption of tetracycline.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
Overdose
No specific antidote. Treatment is supportive and symptomatic, including gastric lavage or induced emesis if recent ingestion.
Pregnancy & Lactation
Contraindicated during pregnancy (especially after 4th month due to tooth discoloration in fetus) and lactation (excreted in breast milk).
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years
Availability
Pharmacies, hospitals
Approval Status
Approved
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensive clinical data available since its introduction in the 1950s, supporting its efficacy in various bacterial infections.
Lab Monitoring
- Renal function tests (for prolonged therapy or renal impairment)
- Liver function tests (for prolonged therapy)
- Complete blood count (periodically for long-term use)
Doctor Notes
- Counsel patients on food/dairy interactions.
- Warn about photosensitivity and advise sun protection.
- Emphasize completing the full course.
Patient Guidelines
- Take with plenty of water.
- Avoid dairy products and antacids.
- Protect skin from sun exposure.
- Complete the full course of antibiotics.
- Do not use if pregnant or breastfeeding.
Missed Dose Advice
If a dose is missed, take it as soon as you remember, unless it is almost time for your next dose. Do not double dose.
Driving Precautions
May cause dizziness or vision disturbances in some individuals; avoid driving or operating machinery if affected.
Lifestyle Advice
- Maintain good oral hygiene.
- Avoid prolonged sun exposure and use sunscreen.
- Inform your doctor about all other medications.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.