Tetrasol
Generic Name
Tetracycline Hydrochloride 25% W/V Solution
Manufacturer
Generic Vet Pharma
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tetrasol 25 w solution | ৳ 125.00 | N/A |
Description
Overview of the medicine
Tetrasol-25-W Solution is a broad-spectrum antibiotic for the treatment of various bacterial infections in poultry, cattle, swine, and other livestock.
Uses & Indications
Dosage
Adults
Poultry: 10-20 mg/kg body weight daily via drinking water for 3-5 days. Cattle/Swine: 10-20 mg/kg body weight daily via drinking water or drench for 3-5 days.
Elderly
No specific dose adjustment for older animals unless severe organ impairment is present.
Renal_impairment
Use with caution; dose reduction may be necessary in severe cases.
How to Take
Administer orally via drinking water. Ensure thorough mixing and that medicated water is the sole source of drinking water during treatment. For individual animals, administer as an oral drench.
Mechanism of Action
Tetracycline inhibits bacterial protein synthesis by reversibly binding to the 30S ribosomal subunit, thereby preventing the attachment of aminoacyl-tRNA to the ribosomal acceptor site. This action is primarily bacteriostatic.
Pharmacokinetics
Onset
Therapeutic levels typically reached within a few hours post-administration.
Excretion
Primarily excreted in urine and bile, with some excretion in feces.
Half life
Varies by animal species, generally 6-12 hours.
Absorption
Good oral absorption; absorption may be decreased by divalent and trivalent cations (e.g., calcium, magnesium, iron).
Metabolism
Partially metabolized in the liver.
Side Effects
Contraindications
- •Animals with known hypersensitivity to tetracyclines.
- •Animals with severe hepatic or renal dysfunction.
- •Young animals during tooth development due to risk of discoloration.
Drug Interactions
Penicillins
May antagonize the bactericidal effect of penicillins when used concurrently.
Iron preparations
Decreased absorption of tetracycline.
Antacids and mineral supplements
May reduce absorption of tetracycline due to chelation.
Storage
Store below 30°C in a dry place, protected from direct sunlight and moisture. Keep out of reach of children and animals.
Overdose
In cases of overdose, supportive and symptomatic treatment should be provided. Reversible renal tubular necrosis has been reported with very high doses.
Pregnancy & Lactation
Use with caution in pregnant or lactating animals. Tetracyclines can cross the placental barrier and are excreted in milk, potentially affecting fetal bone and tooth development.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
2-3 years from the date of manufacture, when stored unopened in original packaging.
Availability
Veterinary pharmacies, agricultural suppliers
Approval Status
Approved for veterinary use
Patent Status
Off-patent
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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