tgdrop
Generic Name
TG Regulator
Manufacturer
MediCo Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tgdrop 100 mg tablet | ৳ 15.00 | ৳ 150.00 |
Description
Overview of the medicine
TGdrop 100 mg Tablet is a medication primarily used to lower high levels of triglycerides in the blood. It works by altering lipid metabolism to reduce the risk of cardiovascular diseases associated with dyslipidemia.
Uses & Indications
Dosage
Adults
Initial dose: 100 mg once daily with food. Max dose: 200 mg once daily.
Elderly
No specific dose adjustment required, but caution advised. Start with a lower dose.
Renal_impairment
CrCl 30-59 mL/min: 50 mg once daily. CrCl <30 mL/min: Not recommended.
How to Take
Take orally, once daily with a main meal to enhance absorption and reduce gastrointestinal discomfort.
Mechanism of Action
TG Regulator acts by activating peroxisome proliferator-activated receptor alpha (PPAR-α), which leads to increased synthesis of lipoprotein lipase and decreased production of apoC-III, thereby enhancing the catabolism of triglyceride-rich lipoproteins (VLDL and chylomicrons) and reducing their plasma levels.
Pharmacokinetics
Onset
Lipid-lowering effects begin within days, maximal effects seen after 2-4 weeks.
Excretion
Mainly excreted in urine (approximately 70%) and feces (approximately 25%) as metabolites.
Half life
Approximately 20 hours.
Absorption
Well absorbed orally, enhanced with food. Peak plasma concentration reached within 2-4 hours.
Metabolism
Primarily metabolized in the liver via glucuronidation.
Side Effects
Contraindications
- •Hypersensitivity to TG Regulator or any component of the tablet
- •Severe renal impairment (CrCl <30 mL/min)
- •Active liver disease or unexplained persistent liver function abnormalities
- •Pre-existing gallbladder disease
Drug Interactions
Statins (e.g., Atorvastatin)
Increased risk of myopathy/rhabdomyolysis.
Oral anticoagulants (e.g., Warfarin)
May potentiate anticoagulant effect, requiring INR monitoring and dose adjustment.
Immunosuppressants (e.g., Cyclosporine)
May impair renal function and increase drug levels.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
No specific antidote. Management involves symptomatic and supportive treatment. Gastric lavage may be considered.
Pregnancy & Lactation
Pregnancy Category C. Use only if potential benefit outweighs risk. Not recommended during breastfeeding due to unknown excretion into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture.
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Patent protected
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Global Brand Names
International brand names for this medicine
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