Administer intramuscularly or intravenously. For intravenous administration, inject slowly over at least 2 minutes. Can be diluted in saline or dextrose solutions.

Timonate acts as a selective dopamine D2 receptor antagonist in the chemoreceptor trigger zone (CTZ) and the gastrointestinal tract, thereby blocking emetic stimuli.

• •Known hypersensitivity to Timonate or any component.
• •Phaeochromocytoma (due to risk of hypertensive crisis).
• •Epilepsy or other conditions predisposing to convulsions.
• •History of tardive dyskinesia from neuroleptics or metoclopramide.
• •Severe hepatic impairment.

Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.

Symptoms may include drowsiness, disorientation, and extrapyramidal reactions. In severe cases, cardiac arrhythmias (including QT prolongation) and seizures may occur. Treatment is symptomatic and supportive. Anticholinergic drugs may be used for extrapyramidal symptoms. Monitor cardiac rhythm.

Use during pregnancy only if clearly needed and the potential benefit outweighs the potential risk. Excreted in breast milk, so caution should be exercised in nursing mothers and consider alternatives or temporary cessation of breastfeeding.