Tolosa
Generic Name
tolosa-80-mg-injection
Manufacturer
MediCorp Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tolosa 80 mg injection | ৳ 8,500.00 | N/A |
Description
Overview of the medicine
Tolosa 80 mg Injection is used for the relief of mild to moderate pain and inflammation.
Uses & Indications
Dosage
Adults
80 mg intramuscularly or by slow intravenous infusion every 8-12 hours, as directed by physician.
Elderly
Lower initial dose and careful monitoring is recommended due to potential for reduced renal function.
Renal_impairment
Dose adjustment required; consult physician.
How to Take
For intramuscular or slow intravenous administration only. Do not administer intra-arterially.
Mechanism of Action
It works by inhibiting the production of prostaglandins, which are chemicals that cause pain and inflammation in the body.
Pharmacokinetics
Onset
15-30 minutes.
Excretion
Excreted mainly through the kidneys.
Half life
Approximately 2-4 hours.
Absorption
Rapidly absorbed after intramuscular or intravenous administration.
Metabolism
Primarily metabolized in the liver.
Side Effects
Contraindications
- •Known hypersensitivity to 'tolosa' or any component of the formulation
- •Active gastrointestinal bleeding or peptic ulcer disease
- •Severe renal or hepatic impairment
- •Third trimester of pregnancy
- •Patients with a history of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
Drug Interactions
Corticosteroids
Increased risk of gastrointestinal ulceration or bleeding.
Diuretics and ACE Inhibitors
Reduced hypotensive effect and increased risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze.
Overdose
Symptoms may include nausea, vomiting, epigastric pain, gastrointestinal bleeding, lethargy, drowsiness, or coma. Management is symptomatic and supportive; consider gastric lavage and activated charcoal if overdose is recent.
Pregnancy & Lactation
Not recommended in the third trimester of pregnancy due to risk of premature closure of the ductus arteriosus. Use with caution in other trimesters and during lactation only if the potential benefit outweighs the potential risk to the fetus/infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Available in pharmacies and hospitals
Approval Status
Approved by DGDA (Bangladesh)
Patent Status
Patent Protected
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Global Brand Names
International brand names for this medicine
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