TopUp
Generic Name
Multivitamin & Multimineral Supplement
Manufacturer
MediHealth Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| topup 5 mg tablet | ৳ 18.00 | ৳ 72.00 |
| topup 10 mg tablet | ৳ 35.00 | ৳ 140.00 |
| topup 20 mg tablet | ৳ 50.00 | ৳ 200.00 |
Description
Overview of the medicine
TopUp is a comprehensive multivitamin and multimineral supplement designed to fulfill daily nutritional requirements and prevent deficiencies.
Uses & Indications
Dosage
Adults
One tablet daily, preferably with a meal or as directed by a physician.
Elderly
One tablet daily, preferably with a meal. Dosage should be individualized based on nutritional needs and existing health conditions; consult a physician.
Renal_impairment
Use with caution and consult a physician due to the risk of mineral accumulation (e.g., potassium, phosphorus, magnesium). Dosage adjustment may be required.
How to Take
Oral, taken with water, preferably after a meal to enhance absorption and reduce gastric upset. Do not crush or chew if it is not a chewable tablet.
Mechanism of Action
Provides essential vitamins and minerals necessary for various metabolic functions, enzyme activity, cellular repair, and overall bodily health.
Pharmacokinetics
Onset
Gradual, benefits accumulate over weeks or months of consistent use.
Excretion
Water-soluble vitamins are primarily excreted via urine; fat-soluble vitamins and their metabolites are primarily excreted via feces/bile.
Half life
Varies greatly by nutrient; water-soluble vitamins typically have short half-lives (hours), while fat-soluble vitamins (A, D, E, K) have longer half-lives (days to months).
Absorption
Varies by specific vitamin/mineral, generally absorbed in the small intestine. Bioavailability can be influenced by food and other dietary components.
Metabolism
Water-soluble vitamins are generally not extensively metabolized before excretion; fat-soluble vitamins are metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation
- Hypervitaminosis (e.g., hypervitaminosis A or D)
- Hemochromatosis or other iron overload disorders
- Severe kidney disease (for certain mineral components)
Drug Interactions
Diuretics (Thiazide diuretics)
Can increase calcium levels; monitor for hypercalcemia if also taking calcium-containing supplements.
Anticoagulants (e.g., Warfarin)
Vitamin K can affect the anticoagulant effect of warfarin. Monitor INR closely.
Thyroid hormones (e.g., Levothyroxine)
Calcium and iron can interfere with levothyroxine absorption. Take thyroid hormones several hours before or after the supplement.
Antibiotics (Tetracyclines, Quinolones)
Minerals like iron, calcium, and zinc can chelate with these antibiotics, reducing their absorption. Administer several hours apart.
Storage
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children. Do not freeze.
Overdose
Symptoms of acute overdose may include nausea, vomiting, stomach upset, diarrhea, headache, and weakness. Chronic high doses, especially of fat-soluble vitamins (A, D, E, K) and certain minerals (e.g., iron, zinc), can lead to toxicity, liver damage, or other serious health issues. In case of suspected overdose, seek immediate medical attention or contact a poison control center.
Pregnancy & Lactation
Generally safe and often recommended to meet increased nutritional needs during pregnancy and lactation. However, it is crucial to consult a doctor or gynecologist before taking any supplement to ensure appropriate dosage and avoid excess levels of certain vitamins (e.g., Vitamin A).
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date
Availability
Pharmacies, supermarkets
Approval Status
Approved as a dietary supplement by DGDA
Patent Status
Not applicable (Generic formulation)
Clinical Trials
While general clinical trials support the efficacy of multivitamin/multimineral supplements in preventing and correcting deficiencies, specific trials for 'TopUp' as a unique brand are not publicly available. The formulation is based on established nutritional science.
Lab Monitoring
- Generally not required for routine use in healthy individuals. May be monitored for specific nutrient levels in cases of confirmed deficiencies, malabsorption syndromes, or during long-term high-dose therapy.
- Liver and kidney function tests may be considered in cases of chronic high dose use or pre-existing conditions affecting nutrient metabolism/excretion.
Doctor Notes
- Emphasize to patients that supplements complement, but do not replace, a healthy diet.
- Advise patients to report any unusual or severe side effects immediately.
- Consider potential interactions with concomitant medications, especially antibiotics, thyroid hormones, and anticoagulants.
Patient Guidelines
- Take the medicine as directed by your healthcare professional or as per the instructions on the packaging.
- Do not exceed the recommended daily dose.
- Keep out of reach of children.
- Store in a cool, dry place away from direct sunlight and moisture.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
TopUp is generally not expected to impair the ability to drive or operate machinery. However, if you experience any side effects like dizziness, avoid such activities.
Lifestyle Advice
- While supplements can help, they are not a substitute for a balanced diet. Strive to eat a variety of fruits, vegetables, whole grains, and lean proteins.
- Regular physical activity and adequate sleep are important for overall health.
- Limit or avoid smoking and excessive alcohol consumption, as these can impair nutrient absorption.
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Global Brand Names
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