Tramp
Generic Name
tramp-325-mg-tablet
Manufacturer
MediCorp Pharmaceuticals
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| tramp 325 mg tablet | ৳ 6.02 | ৳ 60.16 |
Description
Overview of the medicine
Tramp 325 mg Tablet is an analgesic and antipyretic medication used for the relief of mild to moderate pain and fever.
Uses & Indications
Dosage
Adults
1-2 tablets (325-650 mg) every 4-6 hours as needed, not exceeding 8 tablets (2600 mg) in 24 hours.
Elderly
Similar to adult dosage, but caution advised; monitor for renal and hepatic function.
Renal_impairment
Dose adjustment may be necessary in patients with severe renal impairment. Consult a physician.
How to Take
Tramp 325 mg Tablet should be taken orally with water, with or without food.
Mechanism of Action
Tramp is believed to exert its analgesic and antipyretic effects primarily through inhibition of prostaglandin synthesis in the central nervous system.
Pharmacokinetics
Onset
Analgesic and antipyretic effects typically begin within 30-60 minutes.
Excretion
Excreted mainly by the kidneys as metabolites, with a small proportion excreted unchanged.
Half life
The plasma elimination half-life is approximately 2-4 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract, achieving peak plasma concentrations within 30-60 minutes.
Metabolism
Primarily metabolized in the liver via glucuronidation and sulfation pathways.
Side Effects
Contraindications
- Hypersensitivity to Tramp or any component of the formulation
- Severe hepatic impairment
Drug Interactions
Alcohol
Concurrent use with alcohol may increase the risk of hepatotoxicity.
Warfarin
May enhance the anticoagulant effect of warfarin, requiring closer INR monitoring.
Certain Anticonvulsants (e.g., Phenytoin, Carbamazepine)
May reduce the therapeutic effect of Tramp and increase the risk of liver damage.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose may lead to severe hepatotoxicity, renal tubular necrosis, and coma. Management involves symptomatic and supportive treatment, including gastric lavage and administration of appropriate antidotes if available.
Pregnancy & Lactation
Use during pregnancy and lactation should be done with caution and only if clearly needed after consulting a physician.
Side Effects
Contraindications
- Hypersensitivity to Tramp or any component of the formulation
- Severe hepatic impairment
Drug Interactions
Alcohol
Concurrent use with alcohol may increase the risk of hepatotoxicity.
Warfarin
May enhance the anticoagulant effect of warfarin, requiring closer INR monitoring.
Certain Anticonvulsants (e.g., Phenytoin, Carbamazepine)
May reduce the therapeutic effect of Tramp and increase the risk of liver damage.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose may lead to severe hepatotoxicity, renal tubular necrosis, and coma. Management involves symptomatic and supportive treatment, including gastric lavage and administration of appropriate antidotes if available.
Pregnancy & Lactation
Use during pregnancy and lactation should be done with caution and only if clearly needed after consulting a physician.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies nationwide
Approval Status
Approved by regulatory bodies
Patent Status
Patent pending
Clinical Trials
Clinical trials have demonstrated Tramp's efficacy in reducing pain and fever, with a favorable safety profile at recommended doses. Further long-term studies are ongoing.
Lab Monitoring
- Liver function tests (especially in prolonged use or high doses)
- Renal function tests
Doctor Notes
- Emphasize proper dosing and adherence to prevent overdose.
- Advise patients on potential interactions with alcohol and anticoagulants.
- Regularly assess liver and renal function in patients on long-term therapy.
Patient Guidelines
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
- Avoid alcohol consumption while taking this medicine.
- Seek immediate medical attention in case of suspected overdose.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Tramp 325 mg Tablet is generally not expected to impair the ability to drive or operate machinery. However, if you experience dizziness or drowsiness, avoid such activities.
Lifestyle Advice
- Maintain adequate hydration.
- For chronic pain, discuss non-pharmacological pain management strategies with your doctor.
- Avoid self-medication for prolonged periods.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.