Travast
Generic Name
Travoprost ophthalmic solution
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| travast 0004 eye drop | ৳ 470.00 | N/A |
Description
Overview of the medicine
Travoprost is a synthetic prostaglandin F2α analog used to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Uses & Indications
Dosage
Adults
One drop in the affected eye(s) once daily in the evening.
Elderly
No dosage adjustment is required.
Renal_impairment
No dosage adjustment is required.
How to Take
Instill one drop in the conjunctival sac of the affected eye(s). If using other ophthalmic drops, wait at least 5 minutes between applications. After instillation, nasolacrimal occlusion or gentle closing of the eyelid is recommended.
Mechanism of Action
Travoprost is a prostaglandin F2α analog that is a selective FP prostanoid receptor agonist. It works by increasing uveoscleral outflow, thereby reducing intraocular pressure.
Pharmacokinetics
Onset
Within 2 hours
Excretion
Primarily through the kidneys and bile as metabolites.
Half life
Less than 30 minutes for the active free acid in plasma
Absorption
Absorbed through the cornea, where it is hydrolyzed to its active free acid form.
Metabolism
Rapidly metabolized by esterases in the cornea to the biologically active free acid. Further metabolized by beta-oxidation.
Side Effects
Contraindications
- Hypersensitivity to travoprost or any component of the formulation.
Drug Interactions
Systemic drugs
No significant systemic drug interactions are expected due to low systemic absorption.
Other ophthalmic drugs
If using other ophthalmic drops, wait at least 5 minutes between applications.
Storage
Store at room temperature (15°C-25°C), away from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Overdose is unlikely with topical ocular administration. If overdose occurs, treatment should be symptomatic.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution is advised during lactation.
Side Effects
Contraindications
- Hypersensitivity to travoprost or any component of the formulation.
Drug Interactions
Systemic drugs
No significant systemic drug interactions are expected due to low systemic absorption.
Other ophthalmic drugs
If using other ophthalmic drops, wait at least 5 minutes between applications.
Storage
Store at room temperature (15°C-25°C), away from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Overdose is unlikely with topical ocular administration. If overdose occurs, treatment should be symptomatic.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution is advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months (unopened); 4 weeks after opening
Availability
Pharmacies nationwide
Approval Status
Approved
Patent Status
Generic available
Clinical Trials
Information on clinical trials for travoprost is extensively published and supports its efficacy and safety in reducing intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Lab Monitoring
- None specific
Doctor Notes
- Educate patients about the potential for progressive and permanent darkening of iris pigmentation.
- Emphasize the importance of strict adherence to the once-daily dosing regimen for optimal IOP reduction and to minimize systemic side effects.
- Regularly monitor IOP and optic nerve health.
Patient Guidelines
- Remove contact lenses before administration and wait at least 15 minutes before reinserting.
- Avoid touching the dropper tip to the eye or any other surface to prevent contamination.
- Wash hands thoroughly before and after using eye drops.
Missed Dose Advice
If a dose is missed, continue treatment with the next dose as scheduled. Do not exceed one drop daily.
Driving Precautions
May cause temporary blurred vision or discomfort immediately after use. Advise caution when driving or operating machinery until vision is clear.
Lifestyle Advice
- Regular eye check-ups are essential for glaucoma management and monitoring intraocular pressure.
- Report any changes in eye color or vision to your doctor.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.