Trimazole
Generic Name
Trimazole 1% Topical Solution
Manufacturer
MediCare Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| trimazole 1 topical solution | ৳ 68.00 | N/A |
Description
Overview of the medicine
Trimazole 1% Topical Solution is an antifungal medication used to treat various skin infections caused by fungi.
Uses & Indications
Dosage
Adults
Apply thinly to the affected area and surrounding skin 2-3 times daily. Continue for 2-4 weeks or as directed by a healthcare professional, even if symptoms improve.
Elderly
No specific dosage adjustment required; use as per adult dosage.
Renal_impairment
No dosage adjustment necessary due to minimal systemic absorption.
How to Take
For external use only. Clean and dry the affected area before application. Apply a thin layer of the solution and rub it in gently. Wash hands thoroughly after application.
Mechanism of Action
Trimazole inhibits the biosynthesis of ergosterol, a crucial component of fungal cell membranes. This leads to increased permeability and leakage of essential cellular components, ultimately causing fungal cell death.
Pharmacokinetics
Onset
Clinical improvement usually observed within 2-3 weeks, but full course completion is necessary.
Excretion
Primarily excreted via bile and urine, if significant systemic absorption occurs.
Half life
Not well-defined for topical application due to minimal systemic absorption.
Absorption
Minimal systemic absorption through intact skin. Higher absorption may occur through abraded or inflamed skin.
Metabolism
Any systemically absorbed drug is likely metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to trimazole or any other azole antifungals, or to any of the excipients of the solution.
Drug Interactions
No significant drug interactions
Systemic absorption is minimal, therefore, significant drug interactions are unlikely with topical application.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Overdose is unlikely with topical application. In case of accidental ingestion, seek medical attention immediately. No specific antidote is known; treatment is symptomatic and supportive.
Pregnancy & Lactation
Limited data are available on the use of trimazole in pregnant or lactating women. While systemic absorption is minimal, it should be used during pregnancy and lactation only if clearly needed and after consulting a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Available in pharmacies and drugstores
Approval Status
Approved
Patent Status
Off-patent
Clinical Trials
Clinical trials have demonstrated the efficacy and safety of azole antifungals, including hypothetical trimazole, in treating superficial fungal infections. Studies typically involve evaluating mycological cure rates and reduction in clinical symptoms.
Lab Monitoring
- No specific laboratory monitoring is required for topical trimazole solution.
Doctor Notes
- Emphasize patient education on hygiene and adherence to the full treatment course.
- Advise patients to report any severe local reactions or signs of systemic hypersensitivity.
- Consider alternative antifungals or systemic therapy if no improvement after 4 weeks.
Patient Guidelines
- Use only as directed by your doctor or pharmacist.
- Complete the full course of treatment, even if symptoms improve, to prevent recurrence.
- Avoid contact with eyes, mouth, and other mucous membranes. If contact occurs, rinse thoroughly with water.
- Do not cover the treated area with an occlusive dressing unless advised by a doctor.
- Consult a doctor if symptoms do not improve within 2-4 weeks or worsen.
Missed Dose Advice
If a dose is missed, apply it as soon as remembered. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not apply extra medicine to make up for a missed dose.
Driving Precautions
Trimazole topical solution is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Keep the affected area clean and dry.
- Wear loose, breathable clothing to minimize moisture and friction.
- Change socks and underwear frequently if treating foot or groin infections.
- Avoid sharing towels, clothing, or footwear to prevent spreading the infection.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.