Trinon
Generic Name
trinon-0025-cream
Manufacturer
MediCare Pharma Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
trinon 0025 cream | ৳ 46.70 | N/A |
Description
Overview of the medicine
Trinon-0025-Cream contains a mild to moderate potency topical corticosteroid, indicated for the treatment of various inflammatory and pruritic skin conditions like eczema, dermatitis, and psoriasis. It helps reduce redness, swelling, and itching.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected skin area once or twice daily, or as directed by a physician. Gently rub in until the cream disappears.
Elderly
No specific dosage adjustment required; use with caution due to thinner skin.
Renal_impairment
No dosage adjustment required.
How to Take
For external use only. Wash hands before and after applying the cream. Apply a small amount to the affected area and rub in gently. Avoid contact with eyes, mouth, and other mucous membranes. Do not use on broken or infected skin unless advised by a doctor.
Mechanism of Action
The active corticosteroid in Trinon-0025-Cream works by binding to glucocorticoid receptors in the cytoplasm, leading to the activation of anti-inflammatory genes and inhibition of pro-inflammatory mediators. It suppresses the immune response, reduces capillary permeability, and stabilizes lysosomal membranes, thereby exhibiting anti-inflammatory, antipruritic, and vasoconstrictive effects.
Pharmacokinetics
Onset
Symptomatic relief typically begins within a few days of consistent application.
Excretion
Inactive metabolites are excreted mainly by the kidneys.
Half life
Not precisely determined for topical application; systemic half-life depends on the specific corticosteroid if absorbed.
Absorption
Systemic absorption of topical corticosteroids can occur, especially with prolonged use, application to large surface areas, occlusive dressings, or on compromised skin. The extent of absorption varies based on the vehicle, integrity of the epidermal barrier, and age.
Metabolism
Absorbed corticosteroids are metabolized primarily in the liver to inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to any component of the cream
- Untreated bacterial, fungal, or viral skin infections (e.g., herpes simplex, varicella)
- Perioral dermatitis
- Rosacea
- Acne vulgaris
- Perianal and genital pruritus
Drug Interactions
Immunosuppressants
Systemic absorption could potentially lead to additive immunosuppressive effects, although unlikely with topical use.
Other topical corticosteroids
Concurrent use may increase the risk of systemic absorption and side effects.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose with topical application is unlikely. Chronic overuse or misuse may lead to systemic effects such as adrenal suppression (Cushing's syndrome), especially in children or with occlusive dressings. Treatment involves gradual withdrawal of the corticosteroid under medical supervision.
Pregnancy & Lactation
Use during pregnancy and lactation only if the potential benefit outweighs the potential risk to the fetus or infant. Consult a doctor before use. Avoid applying to large surface areas or for prolonged periods.
Side Effects
Contraindications
- Hypersensitivity to any component of the cream
- Untreated bacterial, fungal, or viral skin infections (e.g., herpes simplex, varicella)
- Perioral dermatitis
- Rosacea
- Acne vulgaris
- Perianal and genital pruritus
Drug Interactions
Immunosuppressants
Systemic absorption could potentially lead to additive immunosuppressive effects, although unlikely with topical use.
Other topical corticosteroids
Concurrent use may increase the risk of systemic absorption and side effects.
Storage
Store below 30°C. Protect from light and moisture. Do not freeze. Keep out of reach of children.
Overdose
Acute overdose with topical application is unlikely. Chronic overuse or misuse may lead to systemic effects such as adrenal suppression (Cushing's syndrome), especially in children or with occlusive dressings. Treatment involves gradual withdrawal of the corticosteroid under medical supervision.
Pregnancy & Lactation
Use during pregnancy and lactation only if the potential benefit outweighs the potential risk to the fetus or infant. Consult a doctor before use. Avoid applying to large surface areas or for prolonged periods.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies, Hospitals
Approval Status
Approved (Hypothetical)
Patent Status
Generic available
Clinical Trials
While specific trials for Trinon-0025-Cream are proprietary, active ingredients commonly found in such creams have undergone extensive clinical trials demonstrating their efficacy and safety for indicated skin conditions.
Lab Monitoring
- No routine lab monitoring is generally required for topical corticosteroid use. In cases of extensive or prolonged use, monitoring for systemic effects (e.g., adrenal suppression) might be considered, though it is rare for a 0.025% cream.
Doctor Notes
- Advise patients on proper application technique and emphasize the 'less is more' approach.
- Educate on the potential for local side effects with prolonged use and the importance of adhering to treatment duration.
- Consider differential diagnosis for non-responsive lesions to rule out fungal infections or other dermatoses.
Patient Guidelines
- Use only as directed by your doctor; do not exceed the recommended dose or duration.
- Avoid applying to the face, groin, or armpits unless specifically instructed by your doctor.
- Do not use for longer than the prescribed period, especially on sensitive areas or in children.
- Do not cover the treated area with bandages or other occlusive dressings unless advised by your doctor.
- Inform your doctor if your condition worsens or does not improve after the prescribed treatment period.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Trinon-0025-Cream is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Keep your skin moisturized regularly to help manage dry skin conditions.
- Identify and avoid triggers that worsen your skin condition (e.g., certain soaps, detergents, allergens).
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.