V-Plex
Generic Name
Multivitamin B-complex Injection
Manufacturer
Generic Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| v plex 50 mg injection | ৳ 10.03 | N/A |
Description
Overview of the medicine
V-Plex 50 mg Injection is a multivitamin preparation containing a combination of B-complex vitamins. It is primarily used to prevent and treat deficiencies of these vitamins, which can arise from various conditions such as poor nutrition, certain illnesses, alcoholism, or pregnancy. The B vitamins are essential for various metabolic processes, including energy production, nerve function, and red blood cell formation.
Uses & Indications
Dosage
Adults
Typically 1-2 mL (one vial) intramuscularly or intravenously daily or several times a week, as directed by a physician. Dosage depends on the severity of deficiency.
Elderly
Similar to adult dosage, but caution may be advised in patients with compromised renal function. Physician's discretion is important.
Renal_impairment
No specific dose adjustment is usually required for water-soluble vitamins, but caution with intravenous administration in severe impairment. Consult physician.
How to Take
Administer intramuscularly (IM) or slowly intravenously (IV). For IV administration, it may be diluted in suitable IV fluids (e.g., normal saline, dextrose solution) and infused slowly. Always follow medical professional's instructions.
Mechanism of Action
B vitamins act as coenzymes in various metabolic pathways. Thiamine (B1) is crucial for carbohydrate metabolism. Riboflavin (B2) is essential for cellular respiration. Niacinamide (B3) is involved in fat and carbohydrate metabolism. Pyridoxine (B6) is vital for amino acid metabolism and neurotransmitter synthesis. Cyanocobalamin (B12) and Folic Acid (B9) are essential for DNA synthesis and red blood cell maturation.
Pharmacokinetics
Onset
Relatively rapid, symptoms of deficiency may improve within hours to days, depending on the severity and specific vitamin.
Excretion
Primarily excreted renally (via urine), excess amounts are readily eliminated.
Half life
Varies for each B vitamin; generally short (hours) as they are water-soluble and not extensively stored.
Absorption
Readily absorbed from the injection site (intramuscular or intravenous). Water-soluble vitamins are not extensively stored in the body.
Metabolism
Metabolized in the liver and other tissues to their active coenzyme forms.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation
- Known allergy to any B-vitamins
Drug Interactions
Levodopa
Pyridoxine (B6) can decrease the effectiveness of Levodopa in Parkinson's disease, unless a peripheral decarboxylase inhibitor is also given.
Phenobarbital, Phenytoin
Folic acid may reduce serum concentrations of these anticonvulsants.
Certain antibiotics (e.g., Chloramphenicol)
May interfere with the action of Vitamin B12.
Storage
Store in a cool, dry place, below 25°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
Water-soluble vitamins are generally safe, and excess amounts are excreted. However, extremely high doses of certain individual B vitamins (e.g., Pyridoxine) can lead to neurological toxicity. Treatment is generally supportive and symptomatic.
Pregnancy & Lactation
Generally considered safe and often recommended for supplementation during pregnancy and lactation, especially Folic Acid and B12. However, always consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to any component of the formulation
- Known allergy to any B-vitamins
Drug Interactions
Levodopa
Pyridoxine (B6) can decrease the effectiveness of Levodopa in Parkinson's disease, unless a peripheral decarboxylase inhibitor is also given.
Phenobarbital, Phenytoin
Folic acid may reduce serum concentrations of these anticonvulsants.
Certain antibiotics (e.g., Chloramphenicol)
May interfere with the action of Vitamin B12.
Storage
Store in a cool, dry place, below 25°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
Water-soluble vitamins are generally safe, and excess amounts are excreted. However, extremely high doses of certain individual B vitamins (e.g., Pyridoxine) can lead to neurological toxicity. Treatment is generally supportive and symptomatic.
Pregnancy & Lactation
Generally considered safe and often recommended for supplementation during pregnancy and lactation, especially Folic Acid and B12. However, always consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months from manufacturing date, depending on specific formulation and manufacturer.
Availability
Pharmacies, Hospitals
Approval Status
Approved by health authorities (e.g., DGDA, FDA for similar products)
Patent Status
Generic (Off-patent)
WHO Essential Medicine
YesClinical Trials
Extensive clinical experience supports the efficacy of B-complex vitamins in treating deficiencies. Specific trials for 'V-Plex 50 mg Injection' would be manufacturer-specific, but generally, B-complex formulations are well-established.
Lab Monitoring
- Serum levels of specific B vitamins if deficiency is suspected or for monitoring treatment effectiveness
- Complete Blood Count (CBC) in cases of anemia due to B-vitamin deficiency
Doctor Notes
- Ensure proper technique for IM/IV administration to avoid complications.
- Advise patients on dietary sources of B vitamins and lifestyle modifications.
- Monitor for signs of allergic reaction, especially during initial doses.
Patient Guidelines
- Follow your doctor's instructions strictly regarding dosage and administration.
- Report any unusual or severe side effects to your doctor.
- Do not self-medicate or alter the dosage without medical advice.
- Inform your doctor about all other medications you are taking, including over-the-counter drugs and supplements.
Missed Dose Advice
If a dose is missed, administer it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Generally, V-Plex injection is not expected to impair the ability to drive or operate machinery. However, if you experience dizziness or any other side effect that might affect your concentration, avoid these activities.
Lifestyle Advice
- Maintain a balanced diet rich in fruits, vegetables, and whole grains to ensure adequate B-vitamin intake from food.
- Limit alcohol consumption, as it can deplete B vitamins.
- Regular exercise can support overall health and well-being.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in V-Plex Brand
Other medicines available under the same brand name
V-Plex
Syrup
V-Plex
Tablet
V-Plex Pediatric Drop
Oral Drops
V-Plex
Capsule