Varivax
Generic Name
Varicella Virus Vaccine, Live
Manufacturer
Merck & Co., Inc.
Country
United States
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| varivax 05 ml injection | ৳ 10,823.00 | N/A |
Description
Overview of the medicine
Varivax is a vaccine used to prevent chickenpox (varicella) caused by the varicella zoster virus. It contains a live, attenuated form of the virus.
Uses & Indications
Dosage
Adults
0.5 mL subcutaneously as a 2-dose series, 4-8 weeks apart.
Elderly
Same as adults.
Renal_impairment
No specific dose adjustment needed.
How to Take
Reconstitute lyophilized powder with provided diluent. Administer subcutaneously, preferably in the outer aspect of the upper arm. Do not inject intravenously or intramuscularly.
Mechanism of Action
Induces active immunity against varicella zoster virus by stimulating the production of antibodies and cell-mediated immune responses.
Pharmacokinetics
Onset
Seroconversion usually occurs within 4-6 weeks after vaccination.
Excretion
Not applicable
Half life
Not applicable
Absorption
Not applicable (administered parenterally to elicit immune response)
Metabolism
Not applicable
Side Effects
Contraindications
- Severe allergic reaction (e.g., anaphylaxis) to any component of the vaccine, including gelatin or neomycin.
- Primary or acquired immunodeficiency states.
- Pregnant women.
- Tuberculosis (active, untreated).
- Moderate or severe acute illness.
- Recent receipt of blood products or immunoglobulins.
Drug Interactions
Immunosuppressants
May reduce immune response to vaccine.
Other live vaccines
Administer concurrently or at least 4 weeks apart.
Salicylates (e.g., Aspirin)
Avoid for 6 weeks after vaccination due to risk of Reye's syndrome.
Blood products/Immunoglobulins
May interfere with vaccine efficacy.
Storage
Store and transport refrigerated at 2°C to 8°C (36°F to 46°F). Protect from light. Do not freeze.
Overdose
Overdose is unlikely with vaccines; management would be supportive care for any adverse reactions.
Pregnancy & Lactation
Contraindicated in pregnancy. Avoid pregnancy for 3 months after vaccination. Caution in breastfeeding.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Varies by manufacturer and storage conditions, typically 24-36 months.
Availability
Hospitals, Clinics, Pharmacies
Approval Status
Approved by FDA
Patent Status
Patent protected
Clinical Trials
Extensive clinical trials have demonstrated efficacy and safety in various age groups.
Lab Monitoring
- No routine lab monitoring is required.
Doctor Notes
- Ensure proper cold chain management during storage and transport.
- Screen patients for contraindications before administration.
Patient Guidelines
- Inform your doctor if you have any allergies or a weakened immune system.
- Report any severe reactions after vaccination.
- Avoid close contact with immunocompromised individuals for a few weeks after vaccination.
Missed Dose Advice
If a dose is missed, administer it as soon as possible and reschedule the next dose accordingly.
Driving Precautions
No known effect on driving ability.
Lifestyle Advice
- Maintain good hygiene to prevent spread of infection.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.