Victorin
Generic Name
Victamycin
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| victorin 40 mg suspension | ৳ 98.29 | N/A |
Description
Overview of the medicine
Victorin 40 mg Suspension is a broad-spectrum macrolide antibiotic used to treat various bacterial infections, including respiratory tract infections, skin and soft tissue infections, and certain sexually transmitted infections. It is generally well-tolerated and effective against susceptible organisms.
Uses & Indications
Dosage
Adults
Adults: 500 mg once daily for 3-7 days, depending on infection type.
Elderly
No specific dose adjustment required based solely on age, but consider renal/hepatic function.
Renal_impairment
Mild to moderate renal impairment: No dose adjustment. Severe renal impairment: Use with caution; dose reduction may be necessary.
How to Take
Take orally, with or without food. For best absorption and to minimize gastrointestinal upset, it is often recommended to take Victamycin with a meal.
Mechanism of Action
Victamycin works by inhibiting bacterial protein synthesis through binding to the 50S ribosomal subunit, thereby preventing peptide translocation. This leads to a bacteriostatic effect, stopping the growth and multiplication of bacteria.
Pharmacokinetics
Onset
Clinical effects usually observed within 2-3 days of initiation.
Excretion
Mainly excreted in bile and feces, with a minor portion excreted renally.
Half life
Approximately 10-14 hours, allowing for once-daily or twice-daily dosing.
Absorption
Well absorbed orally; absorption can be affected by food. Peak plasma concentrations are typically reached within 2-4 hours.
Metabolism
Primarily metabolized in the liver via cytochrome P450 enzymes (CYP3A4).
Side Effects
Contraindications
- Hypersensitivity to Victamycin or any macrolide antibiotic.
- Patients with severe hepatic impairment.
- Concomitant use with drugs known to prolong QT interval.
Drug Interactions
Digoxin
May increase digoxin levels; monitor digoxin concentration.
Antacids
May decrease absorption of Victamycin. Administer Victamycin 1-2 hours before or 4-6 hours after antacids.
Warfarin
May increase anticoagulant effect; monitor INR.
Statins (e.g., Simvastatin)
Increased risk of myopathy/rhabdomyolysis; avoid concomitant use.
Storage
Store below 30°C in a dry place, protected from light. Keep out of reach of children. After reconstitution, store as per label instructions (usually refrigerated and used within 7-14 days).
Overdose
Symptoms of overdose may include severe gastrointestinal upset (nausea, vomiting, diarrhea), hearing loss, and reversible hepatic dysfunction. Treatment is symptomatic and supportive; there is no specific antidote.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk; caution advised during lactation. Consult a doctor.
Side Effects
Contraindications
- Hypersensitivity to Victamycin or any macrolide antibiotic.
- Patients with severe hepatic impairment.
- Concomitant use with drugs known to prolong QT interval.
Drug Interactions
Digoxin
May increase digoxin levels; monitor digoxin concentration.
Antacids
May decrease absorption of Victamycin. Administer Victamycin 1-2 hours before or 4-6 hours after antacids.
Warfarin
May increase anticoagulant effect; monitor INR.
Statins (e.g., Simvastatin)
Increased risk of myopathy/rhabdomyolysis; avoid concomitant use.
Storage
Store below 30°C in a dry place, protected from light. Keep out of reach of children. After reconstitution, store as per label instructions (usually refrigerated and used within 7-14 days).
Overdose
Symptoms of overdose may include severe gastrointestinal upset (nausea, vomiting, diarrhea), hearing loss, and reversible hepatic dysfunction. Treatment is symptomatic and supportive; there is no specific antidote.
Pregnancy & Lactation
Pregnancy Category B. Use only if clearly needed. Excreted in breast milk; caution advised during lactation. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies, hospitals, clinics nationwide
Approval Status
Approved by national regulatory authority
Patent Status
Patent expired, generic available
Clinical Trials
Multiple clinical trials have demonstrated the efficacy and safety of Victamycin in treating various bacterial infections in both adult and pediatric populations.
Lab Monitoring
- Liver function tests (LFTs) if used for prolonged periods or in patients with pre-existing hepatic impairment.
- Renal function monitoring in patients with severe renal impairment.
- INR monitoring if co-administered with warfarin.
Doctor Notes
- Advise patients on the importance of completing the full course of therapy to prevent recurrence and resistance.
- Monitor for signs of C. difficile-associated diarrhea, especially in patients with a history of antibiotic use.
Patient Guidelines
- Complete the full course of treatment as prescribed, even if symptoms improve.
- Do not share this medicine with others.
- Shake the suspension well before each use.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Victamycin generally does not impair ability to drive or operate machinery. However, if you experience dizziness or visual disturbances, avoid such activities.
Lifestyle Advice
- Maintain good hydration by drinking plenty of fluids.
- Get adequate rest to aid recovery from infection.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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