Viscon
Generic Name
Fusidic Acid + Hydrocortisone Cream
Manufacturer
Unspecified Manufacturer
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| viscon 15 10 cream | ৳ 40.27 | N/A |
Description
Overview of the medicine
Viscon-15-10 Cream is a combination product containing a corticosteroid (hydrocortisone) and an antibiotic (fusidic acid). It is used to treat inflammatory skin conditions, such as eczema or dermatitis, where bacterial infection is present or likely to occur.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected skin area two to three times daily. Treatment duration should generally not exceed two weeks.
Elderly
No specific dosage adjustments are required for elderly patients, as systemic absorption is minimal.
Renal_impairment
No specific dosage adjustments are required in patients with renal impairment, as systemic absorption is minimal and excretion is primarily non-renal for fusidic acid.
How to Take
Wash hands before and after applying the cream. Apply a thin layer gently to the affected skin area. Avoid contact with eyes, mouth, and other mucous membranes. Do not cover the treated area with bandages or airtight dressings unless advised by a doctor.
Mechanism of Action
Hydrocortisone, a corticosteroid, acts by suppressing the immune response, reducing inflammation, itching, and redness. Fusidic acid is an antibiotic that inhibits bacterial protein synthesis, primarily effective against Gram-positive bacteria, especially Staphylococcus aureus, which commonly causes skin infections.
Pharmacokinetics
Onset
Symptomatic relief often begins within a few days of starting treatment.
Excretion
Fusidic acid and its metabolites are mainly excreted in the bile, with minimal renal excretion. Hydrocortisone metabolites are predominantly excreted via the kidneys.
Half life
After systemic administration, fusidic acid has a plasma half-life of 5-6 hours. Systemic hydrocortisone has a half-life of 8-12 hours; topical data is limited.
Absorption
Systemic absorption of both fusidic acid and hydrocortisone from topical application is limited, but can increase if applied to broken skin, large surface areas, or under occlusive dressings. Fusidic acid penetrates skin well.
Metabolism
Fusidic acid is primarily metabolized in the liver to inactive metabolites. Hydrocortisone is also metabolized in the liver to inactive forms.
Side Effects
Contraindications
- Hypersensitivity to fusidic acid, hydrocortisone, or any other ingredients of the cream.
- Primary skin infections caused by fungi, viruses (e.g., herpes simplex, varicella), or mycobacteria.
- Acne rosacea, perioral dermatitis.
- Ulcerative conditions, atrophic skin.
Drug Interactions
Systemic Corticosteroids
Increased risk of systemic corticosteroid effects if applied to large areas or under occlusion for prolonged periods.
Other Topical Preparations
Avoid using other topical preparations on the same area simultaneously without medical advice to prevent altered absorption or irritation.
Storage
Store below 25°C in a dry place, protected from light. Do not freeze. Keep out of reach of children. Ensure the cap is tightly closed after use.
Overdose
Accidental oral ingestion is unlikely to cause harm due to low systemic absorption. Excessive topical application over large areas or for prolonged periods may lead to systemic corticosteroid effects, such as Cushing's syndrome or adrenal suppression. Management involves symptomatic and supportive measures.
Pregnancy & Lactation
Use with caution during pregnancy and lactation only if the potential benefit justifies the potential risk. Avoid prolonged use or application to large areas, especially near the breasts during breastfeeding. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 to 36 months from the date of manufacture, refer to the product packaging for specific expiry.
Availability
Pharmacies
Approval Status
Approved
Patent Status
Off-patent
Clinical Trials
While specific clinical trial data for 'Viscon-15-10 Cream' may be proprietary, the efficacy and safety of fusidic acid and hydrocortisone combinations are well-established through numerous clinical studies for various inflammatory skin conditions with bacterial infections.
Lab Monitoring
- Not routinely required for short-term topical use. In cases of extensive, prolonged use, especially in children or with occlusive dressings, monitoring for systemic corticosteroid effects (e.g., adrenal function tests like plasma cortisol levels) might be considered.
Doctor Notes
- Emphasize the importance of adherence to prescribed duration of therapy, typically not exceeding two weeks, to minimize corticosteroid-related side effects.
- Counsel patients on avoiding application to the face, intertriginous areas, or under occlusion without specific medical instruction.
- Advise monitoring for signs of secondary infection or lack of improvement, which may necessitate re-evaluation of treatment.
Patient Guidelines
- Use this cream exactly as prescribed by your doctor and for the recommended duration.
- Do not use for longer than two weeks unless specifically advised by your doctor to avoid potential side effects.
- Avoid applying the cream to the face, groin, or armpits unless your doctor has specifically instructed you to do so.
- Wash your hands thoroughly before and after applying the cream.
- Do not cover the treated area with bandages or other airtight dressings unless advised by your doctor, as this can increase absorption.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Viscon-15-10 Cream is a topical preparation and is not expected to affect your ability to drive or operate machinery.
Lifestyle Advice
- Keep the affected skin area clean and dry to aid healing.
- Avoid irritants and harsh soaps that may worsen your skin condition.
- Wear loose-fitting, breathable clothing over treated areas.
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