Vitalex
Generic Name
Cyproheptadine
Manufacturer
Acme Laboratories Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| vitalex 5 mg syrup | ৳ 20.75 | N/A |
Description
Overview of the medicine
Vitalex 5 mg Syrup contains Cyproheptadine, a first-generation antihistamine with antiserotonin and anticholinergic properties. It is primarily used for allergic conditions and as an appetite stimulant.
Uses & Indications
Dosage
Adults
Typical adult dosage for allergic conditions is 5 ml (5 mg) three to four times daily. For appetite stimulation, 5 ml (5 mg) three times daily.
Elderly
Lower doses may be required; caution due to increased susceptibility to side effects.
Renal_impairment
Use with caution; dosage adjustment may be necessary in severe impairment.
How to Take
Administer orally, usually with or without food. Use a measuring spoon or device for accurate dosing.
Mechanism of Action
Cyproheptadine acts as a potent antagonist of histamine H1 receptors. It also possesses serotonin antagonist activity, which is believed to contribute to its appetite-stimulating effect. Additionally, it has anticholinergic effects.
Pharmacokinetics
Onset
Within 15-60 minutes.
Excretion
Mainly excreted in urine, with some in feces.
Half life
Approximately 8 hours.
Absorption
Well absorbed from the gastrointestinal tract.
Metabolism
Extensively metabolized in the liver, primarily by conjugation.
Side Effects
Contraindications
- Hypersensitivity to cyproheptadine or other antihistamines
- Newborns or premature infants
- Nursing mothers
- Glaucoma, prostatic hypertrophy, urinary retention (due to anticholinergic effects)
- Stenosing peptic ulcer
Drug Interactions
MAO Inhibitors
May prolong and intensify the anticholinergic effects of cyproheptadine.
Anticholinergics
Increased risk of anticholinergic side effects.
CNS Depressants (alcohol, sedatives, hypnotics)
Enhanced sedative effects.
Storage
Store below 30°C in a dry place, away from light. Do not freeze.
Overdose
Symptoms include somnolence, coma, convulsions, respiratory depression, hypotension, and circulatory collapse. Treatment is symptomatic and supportive. Gastric lavage and activated charcoal may be considered.
Pregnancy & Lactation
Pregnancy: Category B. Use only if clearly needed. Lactation: Contraindicated, as antihistamines can pass into breast milk and may harm the infant.
Side Effects
Contraindications
- Hypersensitivity to cyproheptadine or other antihistamines
- Newborns or premature infants
- Nursing mothers
- Glaucoma, prostatic hypertrophy, urinary retention (due to anticholinergic effects)
- Stenosing peptic ulcer
Drug Interactions
MAO Inhibitors
May prolong and intensify the anticholinergic effects of cyproheptadine.
Anticholinergics
Increased risk of anticholinergic side effects.
CNS Depressants (alcohol, sedatives, hypnotics)
Enhanced sedative effects.
Storage
Store below 30°C in a dry place, away from light. Do not freeze.
Overdose
Symptoms include somnolence, coma, convulsions, respiratory depression, hypotension, and circulatory collapse. Treatment is symptomatic and supportive. Gastric lavage and activated charcoal may be considered.
Pregnancy & Lactation
Pregnancy: Category B. Use only if clearly needed. Lactation: Contraindicated, as antihistamines can pass into breast milk and may harm the infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24 to 36 months from manufacturing date.
Availability
Pharmacies, Hospitals
Approval Status
Approved in many countries including Bangladesh for symptomatic relief.
Patent Status
Generic available
Clinical Trials
Extensive clinical trials support its efficacy as an antihistamine and appetite stimulant. Newer trials focus on specific populations or off-label uses.
Lab Monitoring
- Periodic blood counts (with prolonged use)
- Liver function tests (if symptoms suggest hepatic involvement)
Doctor Notes
- Counsel patients on potential drowsiness, especially when starting therapy.
- Monitor weight in patients using it as an appetite stimulant.
- Caution in elderly patients due to increased anticholinergic effects.
Patient Guidelines
- Avoid alcohol and other CNS depressants.
- Do not drive or operate machinery until you know how this medicine affects you.
- Report any unusual or severe side effects to your doctor.
- Take exactly as prescribed.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause drowsiness and impair ability to drive or operate machinery. Avoid such activities until you are certain the drug does not cause these effects.
Lifestyle Advice
- Maintain good hydration.
- For appetite stimulation, ensure a balanced diet rich in nutrients.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.