Vitigo-15
Generic Name
Tacrolimus 0.1% Cream
Manufacturer
PharmaCo Inc.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| vitigo 15 cream | ৳ 2,200.00 | N/A |
Description
Overview of the medicine
Vitigo-15 Cream is a topical medication containing Tacrolimus, an immunomodulator, used for the repigmentation of skin in vitiligo patients.
Uses & Indications
Dosage
Adults
Apply a thin layer to affected areas twice daily.
Elderly
Same as adult dosage, use with caution.
Renal_impairment
No specific dosage adjustment required for topical application.
How to Take
For external use only. Apply to clean, dry skin. Wash hands after application. Avoid contact with eyes, nose, and mouth.
Mechanism of Action
Tacrolimus works by inhibiting calcineurin, thereby suppressing T-cell activation and cytokine release, which are implicated in the autoimmune destruction of melanocytes in vitiligo.
Pharmacokinetics
Onset
Repigmentation may start within 3-6 months of consistent use.
Excretion
Biliary and fecal excretion for systemically absorbed drug.
Half life
Not clearly defined for topical use due to minimal systemic absorption.
Absorption
Minimal systemic absorption after topical application.
Metabolism
Primarily hepatic by CYP3A4, but negligible systemically from topical application.
Side Effects
Contraindications
- •Hypersensitivity to Tacrolimus or any component of the cream
- •Immunocompromised patients
Drug Interactions
Live vaccines
Avoid during treatment due to potential immunosuppression.
CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
May increase systemic exposure if significant absorption occurs.
Storage
Store below 30°C. Do not freeze. Keep out of reach of children.
Overdose
Topical overdose is unlikely to cause systemic toxicity due to minimal absorption. If ingested, seek medical attention immediately.
Pregnancy & Lactation
Use only if clearly needed and the potential benefits outweigh the potential risks to the fetus/infant. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date.
Availability
Pharmacies and Hospitals
Approval Status
Approved by major regulatory bodies
Patent Status
Generic available
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Global Brand Names
International brand names for this medicine
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