Voriderm
Generic Name
Prednicarbate
Manufacturer
Incepta Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| voriderm 50 mg tablet | ৳ 40.00 | ৳ 400.00 |
| voriderm 200 mg tablet | ৳ 110.00 | ৳ 1,100.00 |
| voriderm 200 mg injection | ৳ 2,000.00 | N/A |
| voriderm 200 mg suspension | ৳ 1,000.00 | N/A |
Description
Overview of the medicine
Voriderm cream contains Prednicarbate, a synthetic non-halogenated corticosteroid. It is used for the treatment of inflammatory skin conditions such as eczema and psoriasis. Prednicarbate has anti-inflammatory, anti-pruritic, and vasoconstrictive properties.
Uses & Indications
Dosage
Adults
Apply a thin film to the affected skin area once or twice daily. Gently rub in.
Elderly
No specific dose adjustment required; use with caution for prolonged periods.
Renal_impairment
No dose adjustment required.
How to Take
For external use only. Apply thinly to the affected skin area and gently rub in. Do not apply to open wounds or mucous membranes. Wash hands after application.
Mechanism of Action
Prednicarbate acts by inducing phospholipase A2 inhibitory proteins, lipocortins. These proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor, arachidonic acid.
Pharmacokinetics
Onset
Rapid local effect (within hours to days).
Excretion
Excreted mainly in the urine, partly as metabolites.
Half life
Not well defined for topical application; local effect persists for several hours.
Absorption
Minimal systemic absorption through intact skin. Absorption increases with inflammation or occlusion.
Metabolism
Metabolized primarily in the skin and to a lesser extent in the liver.
Side Effects
Contraindications
- Hypersensitivity to prednicarbate or any component of the formulation
- Fungal, viral (e.g., herpes simplex, varicella), or bacterial skin infections
- Perioral dermatitis
- Rosacea
- Acne vulgaris
- Children under 2 years of age
Drug Interactions
Immunosuppressants
Systemic absorption, though minimal, might add to immunosuppressive effects if used extensively.
Other topical corticosteroids
Avoid concomitant use at the same site to prevent additive systemic absorption and local side effects.
Storage
Store below 30°C. Protect from light and moisture. Keep out of the reach of children.
Overdose
Topical overdose is unlikely to produce acute systemic effects. However, prolonged or excessive use of topical corticosteroids can lead to systemic effects such as Cushing's syndrome, hyperglycemia, and suppression of the hypothalamic-pituitary-adrenal (HPA) axis.
Pregnancy & Lactation
Use during pregnancy and lactation only if the potential benefit justifies the potential risk to the fetus or infant, and under strict medical supervision. Avoid large areas or prolonged use.
Side Effects
Contraindications
- Hypersensitivity to prednicarbate or any component of the formulation
- Fungal, viral (e.g., herpes simplex, varicella), or bacterial skin infections
- Perioral dermatitis
- Rosacea
- Acne vulgaris
- Children under 2 years of age
Drug Interactions
Immunosuppressants
Systemic absorption, though minimal, might add to immunosuppressive effects if used extensively.
Other topical corticosteroids
Avoid concomitant use at the same site to prevent additive systemic absorption and local side effects.
Storage
Store below 30°C. Protect from light and moisture. Keep out of the reach of children.
Overdose
Topical overdose is unlikely to produce acute systemic effects. However, prolonged or excessive use of topical corticosteroids can lead to systemic effects such as Cushing's syndrome, hyperglycemia, and suppression of the hypothalamic-pituitary-adrenal (HPA) axis.
Pregnancy & Lactation
Use during pregnancy and lactation only if the potential benefit justifies the potential risk to the fetus or infant, and under strict medical supervision. Avoid large areas or prolonged use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Available in all pharmacies in Bangladesh
Approval Status
DGDA Approved
Patent Status
Generic available
Clinical Trials
Prednicarbate has undergone various clinical trials demonstrating its efficacy and safety in treating inflammatory skin conditions. Studies confirm its moderate potency and good tolerability.
Lab Monitoring
- Not routinely required for localized, short-term topical use. For extensive or prolonged use, HPA axis function monitoring might be considered.
Doctor Notes
- Advise patients on appropriate application technique and duration of use.
- Caution against unsupervised prolonged use, especially in children and on the face.
- Monitor for signs of local skin atrophy or systemic absorption if used extensively.
Patient Guidelines
- Apply only a thin layer to the affected area.
- Do not cover the treated area with occlusive dressings unless advised by a doctor.
- Wash hands thoroughly after application.
- Avoid contact with eyes, mouth, and mucous membranes.
- Do not use for longer than prescribed by your doctor.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
Voriderm cream is unlikely to affect your ability to drive or operate machinery, as it is for topical use only and systemic absorption is minimal.
Lifestyle Advice
- Avoid irritants and allergens that may worsen your skin condition.
- Keep the affected skin clean and moisturized.
- Wear loose, breathable clothing to minimize irritation.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Voriderm Brand
Other medicines available under the same brand name
