X-Pectoran
Generic Name
Bromhexine Hydrochloride
Manufacturer
PharmaCo Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
x pectoran 4 mg syrup | ৳ 40.13 | N/A |
Description
Overview of the medicine
X-Pectoran 4 mg Syrup is a mucolytic agent used to thin and loosen mucus in the airways, making it easier to cough up. It provides relief from productive cough associated with various respiratory conditions.
Uses & Indications
Dosage
Adults
8 mg (10 ml) three times daily. Maximum 24 mg daily.
Elderly
Same as adult dosage, close monitoring for renal/hepatic impairment may be necessary.
Renal_impairment
Reduced dose or extended dose intervals may be required; consult a physician.
How to Take
Take orally, with or without food. Use a measuring spoon or cup for accurate dosing. Shake the bottle well before use.
Mechanism of Action
Bromhexine, the active ingredient, increases serous bronchial secretion and activates ciliated epithelium, leading to improved mucociliary clearance. It depolymerizes mucopolysaccharide fibers, reducing sputum viscosity.
Pharmacokinetics
Onset
Onset of action within 30 minutes to 1 hour.
Excretion
Mainly excreted via the kidneys as metabolites.
Half life
Terminal elimination half-life is about 6.5 hours.
Absorption
Rapidly and almost completely absorbed from the gastrointestinal tract.
Metabolism
Extensive first-pass metabolism in the liver; metabolised to various hydroxylated metabolites, including ambroxol.
Side Effects
Contraindications
- Hypersensitivity to bromhexine or any component of the syrup
- Patients with active peptic ulcer (use with caution)
Drug Interactions
Antibiotics (e.g., Amoxicillin, Cefuroxime)
Bromhexine may increase the penetration of antibiotics into bronchial secretions, potentially enhancing their effect.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Do not freeze.
Overdose
Symptoms of overdose are generally mild and may include gastrointestinal disturbances. Treatment is symptomatic and supportive. Induce emesis or perform gastric lavage if overdose is recent.
Pregnancy & Lactation
Consult a doctor before use during pregnancy or lactation. Use only if clearly needed and the benefit outweighs the potential risk.
Side Effects
Contraindications
- Hypersensitivity to bromhexine or any component of the syrup
- Patients with active peptic ulcer (use with caution)
Drug Interactions
Antibiotics (e.g., Amoxicillin, Cefuroxime)
Bromhexine may increase the penetration of antibiotics into bronchial secretions, potentially enhancing their effect.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Do not freeze.
Overdose
Symptoms of overdose are generally mild and may include gastrointestinal disturbances. Treatment is symptomatic and supportive. Induce emesis or perform gastric lavage if overdose is recent.
Pregnancy & Lactation
Consult a doctor before use during pregnancy or lactation. Use only if clearly needed and the benefit outweighs the potential risk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Pharmacies, drugstores
Approval Status
Approved
Patent Status
Generic available
Clinical Trials
Bromhexine has been evaluated in numerous clinical trials demonstrating its efficacy as a mucolytic agent for various respiratory conditions.
Lab Monitoring
- No specific lab monitoring is typically required for routine use.
Doctor Notes
- Advise patients to maintain adequate hydration.
- Caution in patients with a history of gastric ulcer.
- Monitor for any signs of severe skin reactions and discontinue if they occur.
Patient Guidelines
- Do not exceed the recommended dose.
- If symptoms persist for more than 7 days, consult your doctor.
- Ensure adequate fluid intake to help loosen mucus.
- Keep out of reach of children.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
X-Pectoran 4 mg Syrup is not known to impair the ability to drive or operate machinery.
Lifestyle Advice
- Maintain good hydration by drinking plenty of fluids.
- Avoid smoking and exposure to respiratory irritants.
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Global Brand Names
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