Xepodox
Generic Name
Xepodox
Manufacturer
Example Pharma Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
xepodox 40 mg suspension | ৳ 98.29 | N/A |
xepodox 20 mg pediatric drop | ৳ 60.18 | N/A |
Description
Overview of the medicine
Xepodox is a broad-spectrum third-generation cephalosporin antibiotic used to treat various bacterial infections.
Uses & Indications
Dosage
Adults
200 mg orally twice daily, or as directed by physician.
Elderly
No dose adjustment typically required unless severe renal impairment.
Renal_impairment
Dose adjustment required based on creatinine clearance; e.g., reduce dose for CrCl < 30 mL/min.
How to Take
Administer orally, preferably with food to enhance absorption and reduce gastrointestinal upset. Complete the full course of treatment.
Mechanism of Action
It inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and bacterial death.
Pharmacokinetics
Onset
Within 1-2 hours
Excretion
Primarily excreted unchanged via the kidneys.
Half life
Approximately 2-3 hours
Absorption
Rapidly absorbed after oral administration, bioavailability around 50%.
Metabolism
Minimal hepatic metabolism
Side Effects
Contraindications
- Hypersensitivity to Xepodox or other cephalosporins.
- History of severe hypersensitivity reaction to any beta-lactam antibiotic (e.g., penicillin).
Drug Interactions
0
Antacids/H2-receptor antagonists: May decrease absorption of Xepodox.
1
Probenecid: May increase plasma levels of Xepodox by inhibiting renal excretion.
2
Oral anticoagulants: May enhance the anticoagulant effect.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, seek immediate medical attention. Management includes symptomatic and supportive care. Hemodialysis may be considered in severe cases.
Pregnancy & Lactation
Pregnancy Category B. Use with caution during pregnancy if clearly needed. Excreted in breast milk, so use with caution in lactating mothers.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Available in all pharmacies
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensive clinical trials have demonstrated Xepodox's efficacy and safety in various bacterial infections.
Lab Monitoring
- Monitor renal function, especially in patients with pre-existing renal impairment or during prolonged high-dose therapy.
- Liver function tests may be considered in prolonged use.
Doctor Notes
- Emphasize patient compliance for the full course of treatment.
- Consider renal function adjustment in elderly and renally impaired patients.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Complete the entire course of medication, even if you feel better, to prevent recurrence and resistance.
- Do not share your medication with others.
Missed Dose Advice
If a dose is missed, take it as soon as remembered. If it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose.
Driving Precautions
Xepodox usually does not affect the ability to drive or operate machinery. However, if side effects like dizziness occur, avoid such activities.
Lifestyle Advice
- Stay hydrated by drinking plenty of fluids.
- Maintain good hygiene to prevent infections.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.