Xitob
Generic Name
Tobramycin 0.3% Eye Drop
Manufacturer
Reputable Pharmaceutical Company
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| xitob 03 eye drop | ৳ 95.00 | N/A |
Description
Overview of the medicine
Tobramycin is an aminoglycoside antibiotic used to treat bacterial infections of the eye. It is effective against a wide range of gram-negative and some gram-positive bacteria.
Uses & Indications
Dosage
Adults
Instill 1 or 2 drops into the affected eye(s) every 4 hours. For severe infections, instill 2 drops every hour until improvement, then reduce frequency.
Elderly
No specific dosage adjustment required.
Renal_impairment
No dosage adjustment required for ophthalmic use due to minimal systemic absorption.
How to Take
For ophthalmic use only. Tilt head back, pull down lower eyelid, and instill drops into the conjunctival sac. Avoid touching the dropper tip to the eye or any other surface.
Mechanism of Action
Tobramycin binds to the 30S ribosomal subunit, inhibiting bacterial protein synthesis and leading to bacterial cell death.
Pharmacokinetics
Onset
Rapid, usually within minutes for bacterial inhibition.
Excretion
Primarily excreted unchanged in urine if absorbed systemically.
Half life
Not well-defined for ophthalmic use due to minimal systemic absorption.
Absorption
Minimal systemic absorption from ophthalmic administration.
Metabolism
Not significantly metabolized in the eye; minimal systemic metabolism.
Side Effects
Contraindications
- Hypersensitivity to tobramycin or any component of the formulation.
Drug Interactions
Systemic aminoglycosides
Although minimal systemic absorption, caution with concurrent systemic aminoglycoside use due to potential additive toxicity.
Other ophthalmic medications
If using other eye drops, wait at least 5 minutes between applications.
Storage
Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze.
Overdose
Local ophthalmic overdose can be flushed from the eye with lukewarm water. Systemic overdose is unlikely due to minimal absorption.
Pregnancy & Lactation
Use during pregnancy only if clearly needed. Exercise caution when administering to a nursing woman.
Side Effects
Contraindications
- Hypersensitivity to tobramycin or any component of the formulation.
Drug Interactions
Systemic aminoglycosides
Although minimal systemic absorption, caution with concurrent systemic aminoglycoside use due to potential additive toxicity.
Other ophthalmic medications
If using other eye drops, wait at least 5 minutes between applications.
Storage
Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze.
Overdose
Local ophthalmic overdose can be flushed from the eye with lukewarm water. Systemic overdose is unlikely due to minimal absorption.
Pregnancy & Lactation
Use during pregnancy only if clearly needed. Exercise caution when administering to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months (unopened); discard 28 days after opening.
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Generic available
WHO Essential Medicine
YesClinical Trials
Numerous trials confirm efficacy and safety of tobramycin ophthalmic solution for bacterial eye infections.
Lab Monitoring
- Not typically required for ophthalmic tobramycin.
Doctor Notes
- Emphasize patient compliance for the full course of treatment to prevent resistance.
- Advise patients to seek medical attention if symptoms worsen or persist after recommended treatment duration.
Patient Guidelines
- Do not wear contact lenses during treatment.
- Complete the full course of treatment even if symptoms improve.
- Wash hands before and after use.
Missed Dose Advice
Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Driving Precautions
May cause temporary blurred vision after instillation. Advise patients to avoid driving or operating machinery until vision is clear.
Lifestyle Advice
- Avoid rubbing eyes excessively.
- Maintain good eye hygiene.
Alternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.