Xpa-C
Generic Name
Xpa-C 500 mg Tablet
Manufacturer
MediCare Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| xpa c 500 mg tablet | ৳ 2.50 | ৳ 25.00 |
Description
Overview of the medicine
Xpa-C 500 mg Tablet is used for the relief of mild to moderate pain and to reduce fever. It is a commonly used over-the-counter medication.
Uses & Indications
Dosage
Adults
Oral: 500 mg to 1000 mg every 4-6 hours as needed. Maximum 4000 mg (4 tablets) in 24 hours.
Elderly
No specific dose adjustment is usually required, but caution is advised in patients with impaired renal or hepatic function.
Renal_impairment
Dose adjustment may be necessary. Consult a physician.
How to Take
Take the tablet orally with water, with or without food. Do not exceed the recommended dose.
Mechanism of Action
The exact mechanism of action of Xpa-C is not fully elucidated, but it is believed to involve inhibition of prostaglandin synthesis in the central nervous system, leading to its analgesic and antipyretic effects.
Pharmacokinetics
Onset
Within 30-60 minutes for analgesic and antipyretic effects.
Excretion
Mainly excreted in the urine as glucuronide and sulfate conjugates. A small amount is excreted as unchanged drug.
Half life
1 to 4 hours in adults.
Absorption
Rapidly and almost completely absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 30-60 minutes.
Metabolism
Primarily metabolized in the liver by conjugation with glucuronic acid and sulfate, and also by cytochrome P450 pathway to a minor extent.
Side Effects
Contraindications
- Hypersensitivity to Xpa-C or any component of the formulation
- Severe hepatic impairment or active liver disease
- Glucose-6-phosphate dehydrogenase deficiency
Drug Interactions
Alcohol
Chronic excessive alcohol use may increase the risk of liver damage when taken with Xpa-C.
Warfarin
May enhance the anticoagulant effect of warfarin, increasing the risk of bleeding.
Certain antiepileptics (e.g., carbamazepine, phenytoin)
May increase the metabolism of Xpa-C, potentially reducing its effectiveness.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose can lead to severe liver damage. Symptoms include nausea, vomiting, abdominal pain, and loss of appetite. Seek immediate medical attention. Treatment involves gastric lavage and administration of an antidote like N-acetylcysteine.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation at recommended doses, but always consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to Xpa-C or any component of the formulation
- Severe hepatic impairment or active liver disease
- Glucose-6-phosphate dehydrogenase deficiency
Drug Interactions
Alcohol
Chronic excessive alcohol use may increase the risk of liver damage when taken with Xpa-C.
Warfarin
May enhance the anticoagulant effect of warfarin, increasing the risk of bleeding.
Certain antiepileptics (e.g., carbamazepine, phenytoin)
May increase the metabolism of Xpa-C, potentially reducing its effectiveness.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Overdose can lead to severe liver damage. Symptoms include nausea, vomiting, abdominal pain, and loss of appetite. Seek immediate medical attention. Treatment involves gastric lavage and administration of an antidote like N-acetylcysteine.
Pregnancy & Lactation
Generally considered safe for use during pregnancy and lactation at recommended doses, but always consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from manufacturing date.
Availability
Pharmacies, Hospitals, Clinics
Approval Status
Approved by DGDA
Patent Status
Generic, Patent Expired
WHO Essential Medicine
YesClinical Trials
Extensive clinical data supports the efficacy and safety of Xpa-C as an analgesic and antipyretic. Refer to specific trial publications for details.
Lab Monitoring
- Liver function tests (in cases of prolonged use or suspected overdose)
- Renal function tests (in patients with pre-existing renal impairment)
Doctor Notes
- Counsel patients on maximum daily dose to prevent liver toxicity.
- Advise caution in patients with underlying liver or kidney conditions.
- Educate on symptoms of overdose and need for immediate medical attention.
Patient Guidelines
- Do not exceed the recommended dose.
- Consult a doctor if pain or fever persists for more than a few days.
- Avoid consuming alcohol while taking this medicine.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
Xpa-C is generally not expected to affect the ability to drive or operate machinery. However, if you experience dizziness or drowsiness, avoid such activities.
Lifestyle Advice
- Ensure adequate rest and hydration when experiencing fever.
- For chronic pain, consider physical therapy or other non-pharmacological interventions.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.