Xtracal-D
Generic Name
Calcium Carbonate + Vitamin D3
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| xtracal d 500 mg tablet | ৳ 6.00 | ৳ 60.00 |
Description
Overview of the medicine
Xtracal-D is a combination medication containing Calcium Carbonate and Vitamin D3, primarily used to treat and prevent calcium and vitamin D deficiencies, and for maintaining bone health.
Uses & Indications
Dosage
Adults
1-2 tablets daily, or as directed by physician.
Elderly
Same as adult dosage, or as directed by physician.
Renal_impairment
Use with caution, monitor calcium levels. Dosage adjustment may be required.
How to Take
Oral. Can be taken with or without food, but generally advised with food for better absorption and to reduce gastrointestinal upset.
Mechanism of Action
Calcium carbonate provides elemental calcium essential for bone formation, muscle contraction, nerve function, and blood coagulation. Vitamin D3 (Cholecalciferol) helps in the absorption of calcium from the gut and its deposition in bones.
Pharmacokinetics
Onset
Gradual, for bone health benefits over weeks/months.
Excretion
Calcium is excreted via kidneys and feces. Vitamin D metabolites are excreted primarily in bile/feces.
Half life
Calcium has no true half-life. Vitamin D3 half-life is about 24 hours, but calcifediol (25-OH-D) has a half-life of 2-3 weeks.
Absorption
Calcium is absorbed primarily in the small intestine (15-30%), enhanced by Vitamin D. Vitamin D3 is absorbed from the small intestine and requires bile salts.
Metabolism
Calcium is not metabolized. Vitamin D3 is metabolized in the liver to 25-hydroxyvitamin D (calcifediol) and then in the kidneys to 1,25-dihydroxyvitamin D (calcitriol).
Side Effects
Contraindications
- Hypersensitivity to any component
- Hypercalcaemia
- Severe hypercalciuria
- Kidney stones
- Severe renal impairment
Drug Interactions
Thiazide diuretics
May increase risk of hypercalcaemia.
Digitalis glycosides
Increased risk of arrhythmias due to hypercalcaemia.
Bisphosphonates, Levothyroxine
Calcium can reduce absorption, take 2-4 hours apart.
Tetracycline and Fluoroquinolone antibiotics
Calcium can reduce absorption, take 2-4 hours apart.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms include hypercalcaemia (nausea, vomiting, constipation, thirst, polyuria, muscle weakness, fatigue), hypercalciuria. Management involves stopping treatment, rehydration, and in severe cases, diuretics or corticosteroids.
Pregnancy & Lactation
Generally considered safe and often recommended for supplementation during pregnancy and lactation to meet increased calcium and vitamin D requirements, but should be used under medical supervision.
Side Effects
Contraindications
- Hypersensitivity to any component
- Hypercalcaemia
- Severe hypercalciuria
- Kidney stones
- Severe renal impairment
Drug Interactions
Thiazide diuretics
May increase risk of hypercalcaemia.
Digitalis glycosides
Increased risk of arrhythmias due to hypercalcaemia.
Bisphosphonates, Levothyroxine
Calcium can reduce absorption, take 2-4 hours apart.
Tetracycline and Fluoroquinolone antibiotics
Calcium can reduce absorption, take 2-4 hours apart.
Storage
Store in a cool, dry place, below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
Symptoms include hypercalcaemia (nausea, vomiting, constipation, thirst, polyuria, muscle weakness, fatigue), hypercalciuria. Management involves stopping treatment, rehydration, and in severe cases, diuretics or corticosteroids.
Pregnancy & Lactation
Generally considered safe and often recommended for supplementation during pregnancy and lactation to meet increased calcium and vitamin D requirements, but should be used under medical supervision.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date.
Availability
Pharmacies, drugstores
Approval Status
Approved worldwide
Patent Status
Expired
Clinical Trials
Numerous clinical trials support the efficacy of calcium and vitamin D supplementation for bone health and deficiency prevention.
Lab Monitoring
- Serum calcium levels
- Urinary calcium excretion
- Serum vitamin D levels (especially in long-term use or in patients with renal impairment)
Doctor Notes
- Advise patients on adequate fluid intake.
- Monitor serum calcium levels in patients on long-term therapy or with renal impairment.
Patient Guidelines
- Take as directed by your doctor.
- Do not exceed recommended dose.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Xtracal-D is not known to affect the ability to drive or operate machinery.
Lifestyle Advice
- Maintain a balanced diet rich in calcium and vitamin D.
- Engage in regular weight-bearing exercise.
- Ensure adequate sun exposure for natural vitamin D synthesis.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
Other Medicines in Xtracal-D Brand
Other medicines available under the same brand name
