Xzema
Generic Name
Mometasone Furoate
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| xzema 2 01 cream | ৳ 201.35 | N/A |
Description
Overview of the medicine
Xzema Cream contains Mometasone Furoate, a potent corticosteroid, used to treat inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses such as eczema and psoriasis.
Uses & Indications
Dosage
Adults
Apply a thin film to the affected skin areas once daily.
Elderly
No specific dosage adjustment required; use with caution.
Renal_impairment
No specific dosage adjustment required as systemic absorption is minimal.
How to Take
For topical use only. Apply a thin film to the affected skin once daily and gently rub in.
Mechanism of Action
Mometasone Furoate is a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. It induces phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid.
Pharmacokinetics
Onset
Anti-inflammatory effects usually seen within days.
Excretion
Excreted via urine and feces.
Half life
Systemic half-life not well established due to minimal absorption; eliminated rapidly if absorbed.
Absorption
Minimal systemic absorption through intact skin. Increased absorption with inflamed or damaged skin.
Metabolism
Primarily metabolized in the liver to inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to mometasone furoate or any excipients
- Untreated cutaneous fungal, bacterial, or viral infections
- Rosacea and perioral dermatitis
- Acne vulgaris
Drug Interactions
No significant systemic drug interactions reported.
No significant systemic drug interactions reported.
Storage
Store below 30°C. Do not freeze. Keep out of reach of children.
Overdose
Excessive or prolonged use of topical corticosteroids can suppress pituitary-adrenal function. Management includes gradual withdrawal or substitution with a less potent corticosteroid.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution is advised during lactation.
Side Effects
Contraindications
- Hypersensitivity to mometasone furoate or any excipients
- Untreated cutaneous fungal, bacterial, or viral infections
- Rosacea and perioral dermatitis
- Acne vulgaris
Drug Interactions
No significant systemic drug interactions reported.
No significant systemic drug interactions reported.
Storage
Store below 30°C. Do not freeze. Keep out of reach of children.
Overdose
Excessive or prolonged use of topical corticosteroids can suppress pituitary-adrenal function. Management includes gradual withdrawal or substitution with a less potent corticosteroid.
Pregnancy & Lactation
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Caution is advised during lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies nationwide
Approval Status
Approved by FDA and DGDA
Patent Status
Generic available
Clinical Trials
Numerous clinical trials have established the efficacy and safety of topical mometasone furoate in treating corticosteroid-responsive dermatoses.
Lab Monitoring
- Periodic monitoring for hypothalamic-pituitary-adrenal (HPA) axis suppression may be necessary with extensive or prolonged use.
Doctor Notes
- Advise patients on appropriate application technique.
- Warn about potential for skin thinning with prolonged use, especially on sensitive areas.
- Consider step-down therapy when condition improves.
Patient Guidelines
- Use as directed by your doctor.
- Do not use on face, groin, or underarms unless directed by a doctor.
- Avoid contact with eyes.
- Wash hands before and after application.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not apply a double dose.
Driving Precautions
Xzema Cream is not expected to affect the ability to drive or operate machinery.
Lifestyle Advice
- Avoid irritants that may worsen eczema.
- Keep skin moisturized.
- Wear loose, cotton clothing.
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