Zeenk
Generic Name
Zinc Sulfate Monohydrate
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| zeenk 10 mg syrup | ৳ 32.00 | N/A |
Description
Overview of the medicine
Zeenk (Zinc Sulfate Monohydrate) is a vital trace element essential for numerous bodily functions including immune function, wound healing, DNA synthesis, and proper growth and development. It is used to prevent and treat zinc deficiency.
Uses & Indications
Dosage
Adults
Typically 20-50 mg elemental zinc daily for deficiency, up to 100 mg for specific conditions. Dosage varies based on severity and indication.
Elderly
Similar to adult dosage, but may require careful monitoring due to potential underlying health conditions.
Renal_impairment
No specific dose adjustment required for mild to moderate renal impairment. For severe impairment, consult a physician.
How to Take
Orally, preferably with meals to minimize gastrointestinal upset. However, for maximum absorption, some prefer taking it on an empty stomach if tolerated.
Mechanism of Action
Zinc is a cofactor for over 300 enzymes and is involved in various metabolic processes. It plays a crucial role in immune system regulation, cellular growth, and maintaining structural integrity of proteins and cell membranes.
Pharmacokinetics
Onset
Therapeutic effects are gradual, not immediate, often seen after several days to weeks of supplementation.
Excretion
Primarily excreted via feces, with a small amount excreted in urine and sweat.
Half life
Plasma half-life is approximately 2-3 hours for a single dose, but total body zinc turnover is much longer, reflecting homeostatic control.
Absorption
Absorption is incomplete and varies, typically 20-30% of dietary intake, and is affected by various dietary components.
Metabolism
Not metabolized; primarily distributed throughout the body, with high concentrations in muscle, bone, skin, and hair.
Side Effects
Contraindications
- Hypersensitivity to zinc sulfate or any component of the formulation
Drug Interactions
Penicillamine
Zinc may decrease the absorption of penicillamine. Separate administration by at least 2 hours.
Tetracyclines/Quinolones
Zinc can decrease the absorption of tetracycline and quinolone antibiotics. Administer zinc at least 2 hours before or 4-6 hours after these antibiotics.
Storage
Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of acute overdose include nausea, vomiting, abdominal pain, and diarrhea. Chronic overdose can lead to copper deficiency and anemia. Treatment is supportive.
Pregnancy & Lactation
Considered safe at recommended dietary allowance (RDA) doses during pregnancy and lactation. Higher doses should be used with caution and under medical supervision.
Side Effects
Contraindications
- Hypersensitivity to zinc sulfate or any component of the formulation
Drug Interactions
Penicillamine
Zinc may decrease the absorption of penicillamine. Separate administration by at least 2 hours.
Tetracyclines/Quinolones
Zinc can decrease the absorption of tetracycline and quinolone antibiotics. Administer zinc at least 2 hours before or 4-6 hours after these antibiotics.
Storage
Store in a cool, dry place, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of acute overdose include nausea, vomiting, abdominal pain, and diarrhea. Chronic overdose can lead to copper deficiency and anemia. Treatment is supportive.
Pregnancy & Lactation
Considered safe at recommended dietary allowance (RDA) doses during pregnancy and lactation. Higher doses should be used with caution and under medical supervision.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24-36 months
Availability
Available in pharmacies and hospitals
Approval Status
Approved by DGDA
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Extensively studied in clinical trials, especially regarding its efficacy in treating diarrhea in children and managing zinc deficiency.
Lab Monitoring
- Serum zinc levels (if deficiency suspected or monitoring treatment)
- Serum copper levels (with long-term high-dose zinc therapy)
Doctor Notes
- Confirm zinc deficiency through laboratory tests before initiating high-dose therapy.
- Monitor for signs of copper deficiency in patients on long-term zinc.
Patient Guidelines
- Take with food to reduce stomach upset.
- Do not exceed the recommended dose.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally no specific precautions. However, if you experience side effects like dizziness, avoid driving or operating machinery.
Lifestyle Advice
- Maintain a balanced diet rich in zinc-containing foods like meat, fish, nuts, and whole grains.
- Avoid excessive alcohol consumption, which can impair zinc absorption.
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