Zolaren
Generic Name
Zolarenic Acid 100 mg/5 mL Oral Suspension
Manufacturer
Fictional Pharma Ltd.
Country
Bangladesh
Loading images...
Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| zolaren 1 suspension | ৳ 500.00 | N/A |
Description
Overview of the medicine
Zolaren-1 Suspension is an oral liquid medication containing Zolarenic Acid, a non-steroidal anti-inflammatory drug (NSAID), used for the relief of mild to moderate pain, fever, and inflammation, particularly in children.
Uses & Indications
Dosage
Children
For fever and pain: 5-10 mg/kg body weight, every 6-8 hours as needed, not exceeding 4 doses in 24 hours. Max daily dose 40 mg/kg.
Renal_impairment
Use with caution; dose reduction may be required based on creatinine clearance. Not recommended for severe renal impairment.
How to Take
Administer orally. Shake the bottle well before each use. Use the provided measuring device (syringe or spoon) for accurate dosing.
Mechanism of Action
Zolarenic Acid inhibits prostaglandin synthesis by reversibly blocking cyclooxygenase (COX-1 and COX-2) enzymes. Prostaglandins are key mediators of pain, inflammation, and fever.
Pharmacokinetics
Onset
30-60 minutes for analgesia/antipyresis.
Excretion
Mainly excreted in urine as metabolites, with a small portion excreted in feces.
Half life
Approximately 2-4 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract, peak plasma concentrations typically reached within 1-2 hours.
Metabolism
Primarily metabolized in the liver by oxidation and conjugation.
Side Effects
Contraindications
- Known hypersensitivity to Zolarenic Acid or other NSAIDs
- Active peptic ulcer or gastrointestinal bleeding
- Severe renal or hepatic impairment
- Severe heart failure
- Third trimester of pregnancy
Drug Interactions
Diuretics
May reduce the natriuretic effect of diuretics and increase risk of nephrotoxicity.
Corticosteroids
Increased risk of gastrointestinal ulceration and bleeding.
ACE inhibitors/ARBs
May reduce antihypertensive effect and increase risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep tightly closed.
Overdose
Symptoms include nausea, vomiting, abdominal pain, drowsiness, dizziness. In severe cases, gastrointestinal bleeding, acute renal failure, and CNS depression may occur. Management involves symptomatic and supportive care, gastric lavage or activated charcoal within one hour of ingestion.
Pregnancy & Lactation
Use should be avoided in the third trimester of pregnancy due to risk of premature closure of ductus arteriosus. In early pregnancy and lactation, use only if clearly necessary and potential benefits outweigh risks. Consult a doctor.
Side Effects
Contraindications
- Known hypersensitivity to Zolarenic Acid or other NSAIDs
- Active peptic ulcer or gastrointestinal bleeding
- Severe renal or hepatic impairment
- Severe heart failure
- Third trimester of pregnancy
Drug Interactions
Diuretics
May reduce the natriuretic effect of diuretics and increase risk of nephrotoxicity.
Corticosteroids
Increased risk of gastrointestinal ulceration and bleeding.
ACE inhibitors/ARBs
May reduce antihypertensive effect and increase risk of renal impairment.
Anticoagulants (e.g., Warfarin)
Increased risk of bleeding.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze. Keep tightly closed.
Overdose
Symptoms include nausea, vomiting, abdominal pain, drowsiness, dizziness. In severe cases, gastrointestinal bleeding, acute renal failure, and CNS depression may occur. Management involves symptomatic and supportive care, gastric lavage or activated charcoal within one hour of ingestion.
Pregnancy & Lactation
Use should be avoided in the third trimester of pregnancy due to risk of premature closure of ductus arteriosus. In early pregnancy and lactation, use only if clearly necessary and potential benefits outweigh risks. Consult a doctor.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Pharmacies, Hospitals
Approval Status
Approved by regulatory authorities
Patent Status
Patent Expired
Clinical Trials
Phase I, II, and III clinical trials demonstrated efficacy and safety in pediatric populations for pain and fever reduction. Post-marketing surveillance continues.
Lab Monitoring
- Complete blood count (CBC) with differential if long-term use
- Renal function tests (BUN, creatinine)
- Liver function tests (ALT, AST)
Doctor Notes
- Consider gastroprotective agents if long-term use is necessary, especially in patients with a history of GI issues.
- Monitor renal function, particularly in dehydrated children or those with pre-existing renal conditions.
- Educate parents/caregivers on proper dosing and potential side effects.
Patient Guidelines
- Do not exceed the recommended dose.
- Take with food or milk to minimize stomach upset.
- Inform your doctor if you experience any unusual symptoms.
- Keep out of reach of children.
Missed Dose Advice
If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness or drowsiness. Patients should be cautioned about operating machinery or driving until they know how Zolaren-1 Suspension affects them.
Lifestyle Advice
- Maintain adequate hydration.
- Avoid concomitant use of other NSAIDs.
- Limit alcohol intake.
Alternative Medicines in Bangladesh
Similar medicines available in the market
Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.