Zunex
Generic Name
Zinc Pyrithione 5% w/w Topical Cream
Manufacturer
PharmaCorp Bangladesh Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| zunex 5 w cream | ৳ 30.00 | N/A |
Description
Overview of the medicine
Zunex-5-w-cream is a topical dermatological preparation containing Zinc Pyrithione at 5% w/w. It is primarily used for its antifungal and antiseborrheic properties, helping to manage conditions like seborrheic dermatitis, dandruff, and certain superficial fungal infections of the skin.
Uses & Indications
Dosage
Adults
Apply a thin layer to the affected skin area once or twice daily, or as directed by a physician. Gently massage until absorbed.
Elderly
No specific dosage adjustment required; use as per adult dosage.
Renal_impairment
No specific dosage adjustment required as systemic absorption is minimal.
How to Take
For external use only. Wash and dry the affected area before application. Apply a thin film of cream and rub it gently into the skin. Wash hands thoroughly after application.
Mechanism of Action
Zinc Pyrithione exerts its action by disrupting fungal and bacterial cell membrane integrity, leading to leakage of essential intracellular components and inhibition of cell growth. Its fungistatic and bacteriostatic properties are attributed to its ability to chelate iron and copper ions, thereby interfering with essential metabolic processes in microorganisms.
Pharmacokinetics
Onset
Within a few days of regular application for symptom improvement.
Excretion
Primarily excreted via topical exfoliation; minimal systemic excretion.
Half life
Not well-characterized for topical application due to minimal systemic absorption.
Absorption
Minimal systemic absorption through intact skin. Higher absorption may occur through broken or inflamed skin.
Metabolism
Minimal systemic metabolism due to low absorption.
Side Effects
Contraindications
- Hypersensitivity to Zinc Pyrithione or any components of the cream
- Application to open wounds or severe skin injuries
Drug Interactions
Known systemic drug interactions
Systemic drug interactions are unlikely due to minimal percutaneous absorption. Avoid concomitant application of other topical products on the same area without medical advice.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze.
Overdose
Topical overdose is unlikely to cause systemic toxicity due to minimal absorption. If accidentally ingested, seek medical attention immediately. Local irritation may occur with excessive application.
Pregnancy & Lactation
Use during pregnancy and lactation should be done with caution and only if clearly needed, under medical supervision. Consult a doctor before use.
Side Effects
Contraindications
- Hypersensitivity to Zinc Pyrithione or any components of the cream
- Application to open wounds or severe skin injuries
Drug Interactions
Known systemic drug interactions
Systemic drug interactions are unlikely due to minimal percutaneous absorption. Avoid concomitant application of other topical products on the same area without medical advice.
Storage
Store below 30°C in a dry place, away from direct sunlight. Do not freeze.
Overdose
Topical overdose is unlikely to cause systemic toxicity due to minimal absorption. If accidentally ingested, seek medical attention immediately. Local irritation may occur with excessive application.
Pregnancy & Lactation
Use during pregnancy and lactation should be done with caution and only if clearly needed, under medical supervision. Consult a doctor before use.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months
Availability
Pharmacies, drugstores
Approval Status
Approved
Patent Status
Off-patent
Clinical Trials
Zinc Pyrithione has been extensively studied in clinical trials for its efficacy in dermatological conditions, particularly seborrheic dermatitis and dandruff. The 5% w/w concentration is established as effective.
Lab Monitoring
- No specific lab monitoring is generally required for topical use.
Doctor Notes
- Ensure patients understand 'external use only' and proper application technique.
- Advise patients to report any severe irritation or lack of improvement.
- Consider differential diagnosis for persistent skin conditions.
Patient Guidelines
- For external use only. Avoid contact with eyes, mouth, and other mucous membranes.
- Do not apply on broken or severely irritated skin.
- Discontinue use if irritation or sensitivity develops.
- Keep out of reach of children.
Missed Dose Advice
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose to make up for a missed one.
Driving Precautions
No known effects on ability to drive or operate machinery.
Lifestyle Advice
- Maintain good skin hygiene.
- Avoid harsh soaps or irritants on affected areas.
- Wear loose-fitting clothing to allow skin to breathe.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.