Zylomax
Generic Name
Xylomacin
Manufacturer
PharmaCorp Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| zylomax 500 mg tablet | ৳ 35.00 | N/A |
Description
Overview of the medicine
Zylomax 500 mg Tablet is a broad-spectrum antibiotic used to treat various bacterial infections throughout the body. It works by stopping the growth of bacteria.
Uses & Indications
Dosage
Adults
Typical dosage is 500 mg orally every 12 hours for 5-10 days, depending on the infection severity and type.
Elderly
No specific dosage adjustment is required unless there is significant renal impairment. Use with caution.
Renal_impairment
Dosage adjustment is necessary for patients with creatinine clearance <30 mL/min. Consult a physician for specific guidelines.
How to Take
Take Zylomax 500 mg Tablet orally with a glass of water, with or without food. Do not chew or crush the tablet. It should be taken at regular intervals as prescribed by your doctor.
Mechanism of Action
Xylomacin, the active ingredient in Zylomax, acts by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, repair, and recombination. This leads to bacterial cell death.
Pharmacokinetics
Onset
Within 1-2 hours of administration.
Excretion
Primarily excreted renally (via urine) and to a lesser extent through feces.
Half life
Approximately 3-5 hours.
Absorption
Rapidly and well absorbed from the gastrointestinal tract after oral administration. Bioavailability is approximately 70-80%.
Metabolism
Undergoes limited hepatic metabolism; mainly excreted as unchanged drug.
Side Effects
Contraindications
- Hypersensitivity to Xylomacin or other quinolone antibiotics.
- History of tendinitis or tendon rupture associated with quinolone use.
- Children and adolescents below 18 years of age (due to risk of joint damage).
Drug Interactions
Warfarin
May enhance the anticoagulant effect of warfarin. Monitor INR/PT carefully.
Theophylline
May increase theophylline plasma levels, leading to toxicity. Monitor theophylline levels.
Corticosteroids
Increased risk of tendinopathy and tendon rupture when co-administered.
Iron and Zinc supplements
Can decrease Zylomax absorption. Take Zylomax at least 2 hours before or 6 hours after these supplements.
Antacids containing aluminum or magnesium
Reduce absorption of Zylomax. Administer Zylomax at least 2 hours before or 6 hours after antacids.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of an overdose, symptomatic and supportive treatment should be initiated. Gastric lavage may be performed. Maintain adequate hydration. Hemodialysis or peritoneal dialysis is not effective in removing Xylomacin. Seek immediate medical attention.
Pregnancy & Lactation
Zylomax is generally not recommended during pregnancy (Pregnancy Category C) and lactation due to potential risks to the fetus and infant, including joint damage. Consult your doctor for alternative treatments.
Side Effects
Contraindications
- Hypersensitivity to Xylomacin or other quinolone antibiotics.
- History of tendinitis or tendon rupture associated with quinolone use.
- Children and adolescents below 18 years of age (due to risk of joint damage).
Drug Interactions
Warfarin
May enhance the anticoagulant effect of warfarin. Monitor INR/PT carefully.
Theophylline
May increase theophylline plasma levels, leading to toxicity. Monitor theophylline levels.
Corticosteroids
Increased risk of tendinopathy and tendon rupture when co-administered.
Iron and Zinc supplements
Can decrease Zylomax absorption. Take Zylomax at least 2 hours before or 6 hours after these supplements.
Antacids containing aluminum or magnesium
Reduce absorption of Zylomax. Administer Zylomax at least 2 hours before or 6 hours after antacids.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
In case of an overdose, symptomatic and supportive treatment should be initiated. Gastric lavage may be performed. Maintain adequate hydration. Hemodialysis or peritoneal dialysis is not effective in removing Xylomacin. Seek immediate medical attention.
Pregnancy & Lactation
Zylomax is generally not recommended during pregnancy (Pregnancy Category C) and lactation due to potential risks to the fetus and infant, including joint damage. Consult your doctor for alternative treatments.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from manufacturing date
Availability
Available in pharmacies and hospitals nationwide
Approval Status
Approved by regulatory authorities
Patent Status
Patent expired in most regions
WHO Essential Medicine
YesClinical Trials
Clinical trials have demonstrated Zylomax's efficacy and safety in treating indicated bacterial infections, with response rates comparable to other broad-spectrum antibiotics. Post-marketing surveillance continues to monitor long-term effects.
Lab Monitoring
- Culture and sensitivity testing before initiating treatment to identify susceptible pathogens.
- Renal function tests (serum creatinine, BUN) for patients with pre-existing renal impairment or during prolonged treatment.
- Liver function tests (ALT, AST) if liver dysfunction is suspected or during long-term therapy.
Doctor Notes
- Ensure patient completes the full course to prevent resistance.
- Advise patients on potential CNS and tendon-related adverse effects.
- Check renal function before prescribing, especially in elderly patients.
Patient Guidelines
- Complete the full course of Zylomax as prescribed by your doctor, even if your symptoms improve. Stopping early can lead to antibiotic resistance.
- Avoid self-medication and do not share your medicine with others.
- Stay well-hydrated by drinking plenty of fluids during treatment.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
Zylomax may cause dizziness or lightheadedness. Avoid driving or operating heavy machinery until you know how this medicine affects you.
Lifestyle Advice
- Avoid direct sun exposure and use protective clothing/sunscreen as Zylomax may increase photosensitivity.
- Avoid alcohol consumption during treatment as it may exacerbate side effects.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.