Acos
Generic Name
Acoxacillin
Manufacturer
MediCorp Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| acos 250 mg tablet | ৳ 30.00 | ৳ 180.00 |
Description
Overview of the medicine
Acos 250 mg Tablet contains Acoxacillin, a broad-spectrum penicillin antibiotic used to treat various bacterial infections. It works by inhibiting bacterial cell wall synthesis.
Uses & Indications
Dosage
Adults
250-500 mg every 8 hours, depending on the severity of infection.
Elderly
No specific dose adjustment required unless renal function is impaired.
Renal_impairment
Dose adjustment required; reduce frequency or dose based on creatinine clearance.
How to Take
Can be taken with or without food. Complete the full course of treatment as prescribed by the doctor.
Mechanism of Action
Acoxacillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and bacterial death. It is bactericidal.
Pharmacokinetics
Onset
Within 30-60 minutes.
Excretion
Mainly excreted by the kidneys via tubular secretion and glomerular filtration.
Half life
Approximately 1-1.5 hours.
Absorption
Rapidly absorbed from the gastrointestinal tract; peak plasma concentrations reached within 1-2 hours.
Metabolism
Minimally metabolized; primarily excreted unchanged.
Side Effects
Contraindications
- Hypersensitivity to penicillin or other beta-lactam antibiotics
- History of cholestatic jaundice/hepatic dysfunction associated with penicillin use
Drug Interactions
Probenecid
Increases and prolongs plasma levels of Acoxacillin.
Tetracyclines
May antagonize the bactericidal effect of penicillins.
Oral Contraceptives
May reduce the efficacy of oral contraceptives.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive measures should be taken. Hemodialysis may be beneficial in severe cases.
Pregnancy & Lactation
Category B for pregnancy. Generally considered safe during pregnancy and lactation, but use with caution and under medical supervision.
Side Effects
Contraindications
- Hypersensitivity to penicillin or other beta-lactam antibiotics
- History of cholestatic jaundice/hepatic dysfunction associated with penicillin use
Drug Interactions
Probenecid
Increases and prolongs plasma levels of Acoxacillin.
Tetracyclines
May antagonize the bactericidal effect of penicillins.
Oral Contraceptives
May reduce the efficacy of oral contraceptives.
Storage
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
Overdose
In case of overdose, symptomatic and supportive measures should be taken. Hemodialysis may be beneficial in severe cases.
Pregnancy & Lactation
Category B for pregnancy. Generally considered safe during pregnancy and lactation, but use with caution and under medical supervision.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
24 months from the date of manufacture.
Availability
Available in pharmacies nationwide
Approval Status
Approved by regulatory authorities
Patent Status
Off-patent (fictional)
Clinical Trials
Phase III clinical trials demonstrated efficacy and safety in bacterial infections. Post-marketing surveillance continues.
Lab Monitoring
- Renal function tests (especially in prolonged therapy or pre-existing impairment)
- Liver function tests (rarely)
Doctor Notes
- Counsel patients on importance of completing the full course.
- Advise patients to report any signs of allergic reaction immediately.
- Consider renal function in elderly patients.
Patient Guidelines
- Take the medicine exactly as prescribed.
- Do not stop taking the medicine early, even if you feel better.
- Inform your doctor about any allergic reactions or severe side effects.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Generally does not impair ability to drive or operate machinery. However, if dizziness occurs, caution is advised.
Lifestyle Advice
- Maintain good hydration.
- Avoid alcohol during treatment.
- Report any unusual symptoms promptly.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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