Advixa
Generic Name
Sitagliptin
Manufacturer
Merck Sharp & Dohme (MSD)
Country
USA
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| advixa 40 mg injection | ৳ 8,000.00 | N/A |
Description
Overview of the medicine
Advixa is a DPP-4 inhibitor used to treat type 2 diabetes.
Uses & Indications
Dosage
Adults
100 mg once daily
Elderly
No dosage adjustment needed based on age alone.
Renal_impairment
Dosage adjustment needed for moderate to severe renal impairment.
How to Take
Can be taken with or without food.
Mechanism of Action
Inhibits DPP-4 enzyme, increasing incretin levels, which stimulate insulin release and decrease glucagon levels.
Pharmacokinetics
Onset
Within 1 hour
Excretion
Primarily excreted unchanged in urine
Half life
Approximately 12 hours
Absorption
Rapidly absorbed after oral administration.
Metabolism
Limited metabolism by CYP3A4
Side Effects
Contraindications
- •Hypersensitivity to sitagliptin
- •Type 1 Diabetes Mellitus
Drug Interactions
Digoxin
May increase digoxin levels.
Sulfonylureas
Increased risk of hypoglycemia when used in combination.
Storage
Store at room temperature, away from moisture and heat.
Overdose
In case of overdose, seek immediate medical attention.
Pregnancy & Lactation
Consult a doctor before use during pregnancy and lactation.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 Months
Availability
Pharmacies and hospitals
Approval Status
FDA Approved, DGDA Approved
Patent Status
Expired
WHO Essential Medicine
YesAlternative Medicines in Bangladesh
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Global Brand Names
International brand names for this medicine
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