Aire
Generic Name
Aire-2-mg-tablet
Manufacturer
PharmaCorp Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
Variant | Unit Price | Strip Price |
---|---|---|
aire 2 mg tablet | ৳ 2.00 | ৳ 20.00 |
Description
Overview of the medicine
Aire 2 mg Tablet is an antihistamine used to relieve symptoms of allergy such as runny nose, sneezing, itching, and watery eyes. It can also be used to treat certain skin conditions like eczema or dermatitis.
Uses & Indications
Dosage
Adults
4 mg (two 2 mg tablets) three to four times a day. Maximum recommended dose is 0.5 mg/kg per day.
Elderly
Lower doses may be required; monitor for increased sedation or anticholinergic effects.
Renal_impairment
Use with caution; dose reduction may be necessary in severe impairment.
How to Take
Aire 2 mg Tablet should be taken orally with or without food. It can be taken with food if stomach upset occurs. Do not crush, chew, or break the tablet.
Mechanism of Action
Aire 2 mg Tablet works by blocking the action of histamine, a natural substance in the body that causes allergic symptoms. It selectively blocks H1 histamine receptors, thereby reducing allergic reactions.
Pharmacokinetics
Onset
15-30 minutes
Excretion
Excreted primarily through urine, with some through feces.
Half life
6-9 hours
Absorption
Rapidly absorbed from the gastrointestinal tract.
Metabolism
Extensively metabolized in the liver.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients
- Newborn or premature infants
- Breastfeeding mothers
- Angle-closure glaucoma
- Stenosing peptic ulcer
- Symptomatic prostatic hypertrophy
- Bladder neck obstruction
- Concomitant use with MAO inhibitors
Drug Interactions
Tricyclic Antidepressants
Additive anticholinergic effects.
Atropine and other anticholinergics
Increased risk of anticholinergic side effects.
Monoamine Oxidase Inhibitors (MAOIs)
Prolong and intensify the anticholinergic effects of antihistamines.
CNS Depressants (e.g., alcohol, hypnotics, sedatives)
Increased sedative effect.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, dizziness, ataxia, blurred vision, dry mouth, fixed dilated pupils, flushing, gastrointestinal symptoms, and CNS depression leading to coma. Management involves symptomatic and supportive care. Gastric lavage or activated charcoal may be considered if recent ingestion.
Pregnancy & Lactation
Pregnancy Category B. Use in pregnancy only if clearly needed. Not recommended during breastfeeding due to potential for sedation in infant.
Side Effects
Contraindications
- Hypersensitivity to the active substance or any excipients
- Newborn or premature infants
- Breastfeeding mothers
- Angle-closure glaucoma
- Stenosing peptic ulcer
- Symptomatic prostatic hypertrophy
- Bladder neck obstruction
- Concomitant use with MAO inhibitors
Drug Interactions
Tricyclic Antidepressants
Additive anticholinergic effects.
Atropine and other anticholinergics
Increased risk of anticholinergic side effects.
Monoamine Oxidase Inhibitors (MAOIs)
Prolong and intensify the anticholinergic effects of antihistamines.
CNS Depressants (e.g., alcohol, hypnotics, sedatives)
Increased sedative effect.
Storage
Store in a cool, dry place below 30°C, away from direct sunlight and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include drowsiness, dizziness, ataxia, blurred vision, dry mouth, fixed dilated pupils, flushing, gastrointestinal symptoms, and CNS depression leading to coma. Management involves symptomatic and supportive care. Gastric lavage or activated charcoal may be considered if recent ingestion.
Pregnancy & Lactation
Pregnancy Category B. Use in pregnancy only if clearly needed. Not recommended during breastfeeding due to potential for sedation in infant.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
36 months from the date of manufacture
Availability
Pharmacies nationwide
Approval Status
Approved by DGDA
Patent Status
Generic available
Clinical Trials
Clinical trials have established the efficacy and safety of Aire 2 mg Tablet for its indicated uses. Further studies may explore its broader applications or long-term effects.
Lab Monitoring
- Routine lab monitoring is generally not required for short-term use.
- Monitor complete blood count and liver function tests if used for prolonged periods or in specific high-risk patients.
Doctor Notes
- Counsel patients on potential sedation and avoidance of activities requiring alertness.
- Consider lower doses in elderly patients and those with hepatic/renal impairment.
- Advise against concomitant use with alcohol or other CNS depressants.
Patient Guidelines
- Take the medicine exactly as prescribed by your doctor.
- Do not exceed the recommended dose.
- Avoid driving or operating heavy machinery until you know how this medicine affects you.
- Inform your doctor about all other medications you are taking.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Driving Precautions
This medicine may cause drowsiness and dizziness. Avoid driving, operating machinery, or performing any activity that requires mental alertness until you know how Aire 2 mg Tablet affects you.
Lifestyle Advice
- Avoid alcohol consumption as it can increase drowsiness.
- Stay hydrated to help manage dry mouth.
- Avoid activities requiring mental alertness immediately after taking the medicine.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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