Alben-DS
Generic Name
Albendazole
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| alben ds 400 mg chewable tablet | ৳ 5.00 | ৳ 50.00 |
Description
Overview of the medicine
Albendazole is a broad-spectrum anthelmintic used to treat various worm infestations.
Uses & Indications
Dosage
Adults
400 mg as a single dose. May be repeated after 2 weeks if infection persists.
Elderly
Dosage adjustment may be required based on renal and hepatic function.
Renal_impairment
No specific dosage adjustment guidelines are available. Use with caution.
How to Take
Tablet can be chewed, swallowed whole, or crushed and mixed with food. Take with a fatty meal to enhance absorption.
Mechanism of Action
Albendazole inhibits tubulin polymerization by binding to the colchicine-sensitive site of β-tubulin, resulting in the disruption of microtubules. This causes inhibition of glucose uptake by the worm, leading to its eventual death.
Pharmacokinetics
Onset
Variable, depending on the parasite.
Excretion
Primarily excreted in the urine as metabolites.
Half life
8-12 hours.
Absorption
Poorly absorbed from the gastrointestinal tract; absorption is enhanced with a fatty meal.
Metabolism
Extensively metabolized in the liver to albendazole sulfoxide (active metabolite).
Side Effects
Contraindications
- Hypersensitivity to albendazole or other benzimidazole derivatives
- Pregnancy
Drug Interactions
Praziquantel
May increase plasma concentrations of albendazole.
Dexamethasone
May increase plasma concentrations of albendazole.
Storage
Store below 30°C, away from light and moisture.
Overdose
In case of overdose, symptomatic and supportive treatment should be provided. Activated charcoal may be administered.
Pregnancy & Lactation
Contraindicated in pregnancy. Exercise caution in lactating women.
Side Effects
Contraindications
- Hypersensitivity to albendazole or other benzimidazole derivatives
- Pregnancy
Drug Interactions
Praziquantel
May increase plasma concentrations of albendazole.
Dexamethasone
May increase plasma concentrations of albendazole.
Storage
Store below 30°C, away from light and moisture.
Overdose
In case of overdose, symptomatic and supportive treatment should be provided. Activated charcoal may be administered.
Pregnancy & Lactation
Contraindicated in pregnancy. Exercise caution in lactating women.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years
Availability
Pharmacies and drug stores
Approval Status
DGDA Approved
Patent Status
Off-patent
WHO Essential Medicine
YesClinical Trials
Clinical trials have demonstrated the efficacy of albendazole in treating various helminth infections.
Lab Monitoring
- Liver function tests
- Complete blood count
Doctor Notes
- Monitor liver function during prolonged use.
- Educate patients on hygiene practices to prevent reinfection.
Patient Guidelines
- Take with a fatty meal
- Maintain good hygiene to prevent reinfection
- Complete the full course of treatment
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Driving Precautions
May cause dizziness; use caution when driving or operating machinery.
Lifestyle Advice
- Wash hands frequently
- Wash fruits and vegetables thoroughly
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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