Aldaben
Generic Name
Albendazole
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| aldaben 200 mg suspension | ৳ 20.00 | N/A |
Description
Overview of the medicine
Albendazole is a broad-spectrum anthelmintic used to treat a variety of worm infestations.
Uses & Indications
Dosage
Adults
400 mg as a single dose for ascariasis, hookworm, whipworm, and pinworm infections. For hydatid disease, 400 mg twice daily for 28 days, repeated as needed.
Elderly
No specific dosage adjustments are necessary for elderly patients, but caution should be exercised due to potential age-related decline in organ function.
Renal_impairment
No specific dosage adjustments are necessary for patients with renal impairment.
How to Take
May be taken with or without food, but absorption is improved with a fatty meal. Chewable tablets should be chewed thoroughly before swallowing.
Mechanism of Action
Albendazole inhibits tubulin polymerization, disrupting microtubule-dependent glucose uptake in susceptible helminths.
Pharmacokinetics
Onset
Variable, depending on parasite burden and individual metabolism.
Excretion
Primarily excreted in the urine as metabolites.
Half life
8-12 hours
Absorption
Poorly absorbed from the GI tract; absorption increased when administered with a fatty meal.
Metabolism
Extensively metabolized in the liver to albendazole sulfoxide (active metabolite).
Side Effects
Contraindications
- Hypersensitivity to albendazole or other benzimidazole derivatives.
- Pregnancy
Drug Interactions
Praziquantel
May increase plasma levels of albendazole.
Dexamethasone
May increase plasma levels of albendazole.
Storage
Store below 30°C (86°F), away from light and moisture.
Overdose
In case of overdose, supportive and symptomatic treatment should be provided.
Pregnancy & Lactation
Contraindicated in pregnancy. Caution should be exercised when administering albendazole to a nursing woman.
Side Effects
Contraindications
- Hypersensitivity to albendazole or other benzimidazole derivatives.
- Pregnancy
Drug Interactions
Praziquantel
May increase plasma levels of albendazole.
Dexamethasone
May increase plasma levels of albendazole.
Storage
Store below 30°C (86°F), away from light and moisture.
Overdose
In case of overdose, supportive and symptomatic treatment should be provided.
Pregnancy & Lactation
Contraindicated in pregnancy. Caution should be exercised when administering albendazole to a nursing woman.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
3 years
Availability
Pharmacies and medical stores
Approval Status
DGDA Approved
Patent Status
Off-Patent
WHO Essential Medicine
YesClinical Trials
Several clinical trials have demonstrated the efficacy of albendazole in treating various worm infestations.
Lab Monitoring
- Complete blood count
- Liver function tests
Doctor Notes
- Consider alternative treatments in patients with pre-existing liver disease.
- Monitor liver function tests periodically during long-term therapy.
Patient Guidelines
- Take the medicine as directed by your doctor.
- Complete the full course of treatment, even if you feel better.
- Inform your doctor if you experience any unusual side effects.
Missed Dose Advice
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Driving Precautions
May cause dizziness; use caution when driving or operating machinery.
Lifestyle Advice
- Maintain good hygiene to prevent reinfection.
- Wash your hands frequently, especially after using the toilet and before preparing food.
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Global Brand Names
International brand names for this medicine. Click a brand to search for detailed information.
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