Alercon
Generic Name
Naphazoline Hydrochloride + Antazoline Phosphate Eye Drop
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| alercon 01 eye drop | ৳ 105.00 | N/A |
Description
Overview of the medicine
Alercon-01 Eye Drop is an ophthalmic solution containing Naphazoline Hydrochloride and Antazoline Phosphate, used for the relief of allergic conjunctivitis symptoms such as redness, itching, and watering of the eyes.
Uses & Indications
Dosage
Adults
1-2 drops in the affected eye(s) up to 3-4 times daily.
Elderly
Same as adult dosage. Use with caution in patients with cardiovascular disease or glaucoma.
Renal_impairment
No specific dosage adjustment required as systemic absorption is minimal.
How to Take
For ophthalmic use only. Tilt head back, pull down lower eyelid to form a pocket, instil drops, and gently close eye. Do not touch dropper tip to any surface.
Mechanism of Action
Naphazoline acts as a sympathomimetic amine, causing vasoconstriction and reducing ocular redness. Antazoline is an H1-receptor antagonist (antihistamine) that blocks histamine action, thereby relieving itching and watery eyes associated with allergic reactions.
Pharmacokinetics
Onset
Rapid, typically within minutes.
Excretion
Not extensively studied for topical ophthalmic route; primarily local elimination. Any absorbed systemic drug is excreted renally.
Half life
Not well-defined for topical ophthalmic use due to minimal systemic absorption; local effect duration is a few hours.
Absorption
Minimal systemic absorption after ocular administration. Local absorption into ocular tissues.
Metabolism
Primarily local metabolism in ocular tissues; systemic metabolism (if any significant absorption occurs) is hepatic.
Side Effects
Contraindications
- Hypersensitivity to Naphazoline, Antazoline, or any component of the formulation.
- Narrow-angle glaucoma.
- Use with MAO inhibitors.
Drug Interactions
Beta-blockers
May reduce the vasoconstrictive effect of naphazoline.
MAO Inhibitors
Concurrent use with MAO inhibitors can lead to hypertensive crisis due to enhanced sympathomimetic effects.
Storage
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
Systemic overdose is unlikely with ophthalmic use. If accidentally ingested, symptoms may include drowsiness, sweating, hypotension, or coma (especially in children). Seek immediate medical attention.
Pregnancy & Lactation
Use with caution. Consult a doctor. Data on safety during pregnancy and lactation are limited. Systemic absorption is minimal, but risks should be weighed against benefits.
Side Effects
Contraindications
- Hypersensitivity to Naphazoline, Antazoline, or any component of the formulation.
- Narrow-angle glaucoma.
- Use with MAO inhibitors.
Drug Interactions
Beta-blockers
May reduce the vasoconstrictive effect of naphazoline.
MAO Inhibitors
Concurrent use with MAO inhibitors can lead to hypertensive crisis due to enhanced sympathomimetic effects.
Storage
Store below 30°C. Protect from light. Do not freeze. Keep out of reach of children.
Overdose
Systemic overdose is unlikely with ophthalmic use. If accidentally ingested, symptoms may include drowsiness, sweating, hypotension, or coma (especially in children). Seek immediate medical attention.
Pregnancy & Lactation
Use with caution. Consult a doctor. Data on safety during pregnancy and lactation are limited. Systemic absorption is minimal, but risks should be weighed against benefits.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 24-36 months unopened; 28 days after opening.
Availability
Pharmacies
Approval Status
Approved
Patent Status
Off-patent
Clinical Trials
Extensively studied and widely used for many decades; newer trials may focus on combination therapies or novel formulations.
Lab Monitoring
- No specific lab monitoring is typically required for ophthalmic Naphazoline/Antazoline.
Doctor Notes
- Advise patients on proper instillation technique to avoid contamination.
- Warn against prolonged use due to risk of rebound hyperemia.
Patient Guidelines
- Do not use if solution changes color or becomes cloudy.
- Remove contact lenses before use and wait at least 15 minutes before reinserting.
- Avoid touching the dropper tip to any surface to prevent contamination.
Missed Dose Advice
If a dose is missed, apply it as soon as remembered. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.
Driving Precautions
May cause temporary blurred vision or pupil dilation. Avoid driving or operating machinery until vision clears.
Lifestyle Advice
- Avoid known allergens to reduce symptoms.
- Do not rub eyes, as this can worsen irritation.
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