Amboten
Generic Name
Ambroxol Hydrochloride
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| amboten 15 mg syrup | ৳ 50.00 | N/A |
Description
Overview of the medicine
Ambroxol is a mucolytic agent used to treat acute and chronic respiratory diseases associated with abnormal mucus secretion and impaired mucus transport. It works by thinning and loosening mucus in the airways, making it easier to cough out.
Uses & Indications
Dosage
Adults
10 ml (30 mg) three times daily or as directed by physician.
Elderly
No specific dosage adjustment needed for elderly patients, generally follow adult dosage.
Renal_impairment
Use with caution in severe renal impairment; dose reduction may be necessary.
How to Take
Amboten syrup should be taken orally, with or without food. Measure the dose using a measuring spoon or cup provided with the syrup.
Mechanism of Action
Ambroxol works by stimulating serous glandular cells, leading to increased production of low-viscosity mucus. It also depolymerizes mucopolysaccharides, reducing the viscosity of mucus and aiding in its clearance from the respiratory tract. It also has secretomotoric activity.
Pharmacokinetics
Onset
Approximately 30 minutes
Excretion
Mainly via the kidneys, with approximately 90% of the dose excreted renally.
Half life
About 7-12 hours
Absorption
Rapidly and almost completely absorbed after oral administration, with peak plasma concentrations occurring within 1-2.5 hours.
Metabolism
Primarily in the liver via first-pass metabolism, forming inactive metabolites.
Side Effects
Contraindications
- Hypersensitivity to Ambroxol or any component of the formulation
- Patients with rare hereditary conditions of fructose intolerance (due to sorbitol content in some formulations)
Drug Interactions
Antibiotics
Concurrent administration of Ambroxol with antibiotics (e.g., amoxicillin, cefuroxime, erythromycin, doxycycline) may lead to increased concentration of antibiotics in bronchopulmonary secretions.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, diarrhea, and abdominal pain. Treatment is symptomatic and supportive; no specific antidote is known. Gastric lavage or emesis may be considered.
Pregnancy & Lactation
Use during pregnancy (especially first trimester) and lactation only if clearly necessary and after careful risk-benefit assessment by a physician. Ambroxol passes into breast milk.
Side Effects
Contraindications
- Hypersensitivity to Ambroxol or any component of the formulation
- Patients with rare hereditary conditions of fructose intolerance (due to sorbitol content in some formulations)
Drug Interactions
Antibiotics
Concurrent administration of Ambroxol with antibiotics (e.g., amoxicillin, cefuroxime, erythromycin, doxycycline) may lead to increased concentration of antibiotics in bronchopulmonary secretions.
Storage
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.
Overdose
Symptoms of overdose include nausea, vomiting, diarrhea, and abdominal pain. Treatment is symptomatic and supportive; no specific antidote is known. Gastric lavage or emesis may be considered.
Pregnancy & Lactation
Use during pregnancy (especially first trimester) and lactation only if clearly necessary and after careful risk-benefit assessment by a physician. Ambroxol passes into breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from the date of manufacture, specific details on packaging.
Availability
Pharmacies nationwide
Approval Status
Approved in Bangladesh
Patent Status
Generic available, original patent expired
Clinical Trials
Numerous clinical trials have demonstrated the efficacy of Ambroxol as a mucolytic and its safety profile in various respiratory conditions. Ongoing research explores its anti-inflammatory and antioxidant roles.
Lab Monitoring
- No routine lab monitoring is generally required for Ambroxol.
Doctor Notes
- Advise patients about the importance of adequate hydration.
- Monitor for signs of allergic reactions, especially severe skin reactions.
- Consider dose adjustment in severe renal impairment.
Patient Guidelines
- Always follow your doctor's instructions regarding dose and duration.
- Do not exceed the recommended dose.
- Inform your doctor if your condition worsens or does not improve.
Missed Dose Advice
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Driving Precautions
Ambroxol is not known to impair the ability to drive or operate machinery. However, if you experience side effects like dizziness, avoid such activities.
Lifestyle Advice
- Maintain good hydration by drinking plenty of fluids, as this helps to thin mucus.
- Avoid smoking and exposure to irritants that may worsen respiratory conditions.
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Global Brand Names
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