Ambronil
Generic Name
ambronil-15-mg-syrup
Manufacturer
Square Pharmaceuticals Ltd.
Country
Bangladesh
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Price Details
Current market pricing information
| Variant | Unit Price | Strip Price |
|---|---|---|
| ambronil 15 mg syrup | ৳ 50.00 | N/A |
Description
Overview of the medicine
Ambronil 15 mg Syrup contains Ambroxol Hydrochloride, a mucolytic agent used to thin and loosen mucus in the airways, making it easier to cough up. It is used to relieve productive cough associated with various respiratory conditions.
Uses & Indications
Dosage
Adults
10 mL (30 mg) 3 times daily, or 5 mL (15 mg) 2-3 times daily.
Elderly
No specific dose adjustment required, but caution with renal/hepatic impairment.
Renal_impairment
Dosage adjustment may be necessary; consult a physician.
How to Take
Oral administration. Take with or without food. Use a measuring spoon/cup for accurate dosage.
Mechanism of Action
Ambroxol acts as a mucolytic agent by depolymerizing mucopolysaccharides in bronchial secretions, leading to liquefaction of mucus. It also stimulates the production of pulmonary surfactant, which helps to stabilize the alveoli and promote mucociliary clearance.
Pharmacokinetics
Onset
Within 30 minutes
Excretion
Mainly excreted renally (approximately 90%) as metabolites, with a small portion excreted unchanged.
Half life
Approximately 10 hours
Absorption
Rapidly and almost completely absorbed from the GI tract.
Metabolism
Undergoes extensive first-pass metabolism in the liver to various inactive metabolites.
Side Effects
Contraindications
- •Hypersensitivity to Ambroxol or any component of the formulation
- •Patients with rare hereditary conditions of fructose intolerance (due to sorbitol content)
Drug Interactions
Antitussives (cough suppressants)
Concurrent use may lead to a dangerous accumulation of bronchial secretions due to inhibition of the cough reflex.
Antibiotics (e.g., amoxicillin, cefuroxime, erythromycin, doxycycline)
Ambroxol can increase the concentration of antibiotics in bronchial secretions, potentially enhancing their therapeutic effect.
Storage
Store below 30°C in a dry place, away from light. Do not freeze. Keep out of reach of children.
Overdose
Symptoms of overdose are generally mild and may include nausea, vomiting, diarrhea, and dyspepsia. Treatment is symptomatic and supportive; gastric lavage may be considered in severe cases.
Pregnancy & Lactation
Use in pregnancy (especially first trimester) and lactation only if clearly necessary and under medical supervision. Ambroxol crosses the placental barrier and is excreted in breast milk.
Frequently Asked Questions
Common questions about this medicine
Pack Sizes
Shelf Life
Typically 2-3 years from manufacturing date, check packaging.
Availability
Pharmacies, Hospitals
Approval Status
Approved by DGDA
Patent Status
Generic available
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Global Brand Names
International brand names for this medicine
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